"KROK 2. PHARMACY" Materials for self-preparing for license exam - (discipline - clinical pharmacy)
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
1
Materials
for self-preparing
for license exam
"KROK 2. PHARMACY"
(discipline – clinical pharmacy)
faculty for foreign citizens’ education2
Introduction in Clinical Pharmacy
Which of the listed preparations should be Which drug of the given below is a
used as antidote and included into the first- first aid antidote for acute poisoning
aid kit required at factories where acute caused by arsenic, mercury,
intoxications with arsenic, mercury, chromium, and bismuth
chrome and bismuth compounds are compounds?
possible? A. Dimercaprol (Unithiol)
A. Unithiolum B. Prednisolone
B. Аdrenalinum C. Atropine
C. Аtropinum D. Adrenaline
D. Morphinum E. Morphine
E. Droperidolum
A 38-year-old male patient with Treatment of poisonings with inorganic
mercuric chloride intoxication has been mercury compounds includes the use of
delivered to the admission ward in grave the following antidote:
condition. What antidote must be A. Unithiol
immediately administered the patient? B. Naloxone
A. Unithiol C. Tetacinum-calcium
B. Dipyroxime D. Desferal
C. Atropine E. Dexamethasone
D. Nalorphine
E. Izonitrozinum
A patient with chronic heart failure, who has During the treatment of chronic heart
been taking cardiac glycosides, developed signs failure with digoxin in a patient having
of glycoside intoxication. What antidote would bradycardia, nausea, vomiting, blurred
be advisable in this case? vision. Which drug is the antidote in
A. Unithiol (DMPS) this case?
B. Vicasol (Menadione) A. Unithiol (2,3-Dimercapto-l-
C. Protamine propanesul-fonic acid)
D. Naloxone B. Tetacinum calcium
E. Methionine C. Dipiroximum
D. Amyl nitrite
E. Atropine sulphate
A child has accidentally drunk a solution that A patient suffering from trombophlebitis
was used by his grandmother for glaucoma of his lower extremities has developed
treatment. The solution turned out to be symptoms of heparin overdosage. What
pilocarpine hydrochloride. What drug can be drug can be used as an antidote?
used as an antidote? A. Protamine sulfate
A. Аtropinum B. Phenindione (Phenylin)
B. Carbacholinum C. Dipiridamol
C. Aceclidinum D. Pentoxifylline
D. Веnzohexonium E. Theophylline
E. Реntaminum
A patient receives heparin for acute myocardial A patient receives heparin for acute
infarction. On the third day the patient myocardial infarction. On the third day the
developed hematuria and subcutaneous patient developed hematuria and3
hematomas. What medicine should be subcutaneous hematomas. What medicine
prescribed as an antidote in this case? should be prescribed as an antidote in this
A. Protamine sulfate case?
B. Vicasol (Menadione) A. Protamine sulfate
C. Streptokinase B. Pancreatin
D. Clopidogrel C. Streptokinase
E. Acetylsalicylic acid D. Clopidogrel
E. Acetylsalicylic acid
A patient with signs of morphine What preparation is the specific antidote
intoxication has been delivered into an in case of intoxication with iron
admission room. Name the necessary preparations?
antidote: A.Deferoxamium
A. Naloxone B. Protamine sulfate
B. Collargol C. Bemegridum
C. Essentiale D.Atropinum
D. Ectericidum E. Penicillamine
E. Trental (Pentoxifylline)
Which drug with antagonistic effect can be A 45-year-old patient has been taking
used to stop bleeding caused by prolonged neodicumarinum for thrombophlebitis
use of neodicumarinum? for two weeks. The regular blood test
A. Vikasolum revealed a decrease in prothrombin
B. Aminocapronic acid concentration, microhematuria. Which
C. Etamsylate drug should be used as neodicumarinum
D. Fibrinoge antagonist?
E. Ascorbic acid A. Vicasol
B. Protamine sulfate
C. Sodium citrate
D. Heparin
E. Aminocaproic acid
During a surgical operation the muscle A 5-year-old child had accidentally
relaxant tubocurarine chloride was used. drunk a bottle of eye drops. After 30
What antagonist drug should be injected in minutes the child developed shortness
order to allow the patient to brief of breath, difficult swallowing, voice
independently? hoarseness, dilated pupils,
A. Neostigmine hyperthermia. Which of the drugs might
B. Dithylinum have induced the described
C. Cytitonum manifestations?
D. Aethimizolum A. Atropine
E. Веnzohexonium B. Adrenaline
C. Mesatonum
D. Pilocarpine
E. Novocaine
A woman who has been treated for After the start of a treatment, a
infiltrative focal tuberculosis for a long tuberculosis patient has developed red
time complains of acute hearing coloration of urine, saliva, and lacrimal
impairment. Which of the following fluid. What drug could have caused4
preparations might be the cause of this side such changes in this case?
effect? A. Rifampicin
A. Streptomycin B. Alcoholic iodine solution
B. Isoniazid C. Isoniazid
C. Ethambutol D. Ciprofloxacin
D. Rifampicin E. Benzylpenicillin (Penicillin G)
E. Ethionamidum sodium salt
A woman with open tuberculosis is undergoing For treatment of enteric infection a 36-
in-patient treatment in the tuberculosis clinic. year-old woman was prescribed a
What drug was prescribed by her physician for nitrofuran derivative that is poorly
etiotropic treatment? absorbed in the intestine and takes its effect
A. Isoniazid along the intestinal tract. Name this drug:
B. Acyclovir A. Nifuroxazide
C. Metronidazole B. Furacilin (Nitrofural)
D. Doxycycline hydrochloride C. Nitroxoline
E. Benzylpenicillin (Penicillin G) D. Furadonin (Nitrofurantoin)
E. Nalidixic acid
From the pharmaceutical stock select a What antiprotozoal agent can be
reversible anticholinesterase drug to be recommended to a female patient with
administered to the patients with atony of trichomoniasis?
the intestine and urinary bladder in the A. Metronidazole
postoperative period: B. Primaquine
A. Proserin C. Chloridinum
B. Phosphacolum D. Solusurminum
C. Benzohexonium E. Chiniofonum
D. Atropine sulfate
E. Dithylinum
After a craniocerebral trauma a patient was A patient suffering from neurosis
administered pyracetam. This drug relates to accompanied by anxiety and fear
the following pharmacological group: development was prescribed diazepam.
A. Nootropic agent What pharmacological effect makes it
B. Nonnarcotic (nonopioid) analgetic possible to apply the drug for this disease
C. Tranquilizers treatment?
D. Anesthetic agent A. Anxiolytic
E. Neuroleptic B. Antiarrhythmic
C. Anti-inflammatory
D. Hypotensive
E. Antianginal
What antibiotic has beta-lactam cycle in its At the end of the dug action drug
structure? addicts develop severe mental,
A. Benzylpenicillin potassium salt neurological and somatic disorders.
B. Doxycycline hyclate This complex of symptoms is called:
C. Chloramphenicol A. Withdrawal syndrome
D. Streptomycin sulfate B. Tachyphylaxis
E. Lincomycin hydrochloride C. Sensibilization
D. Cumulation5
E. Tolerance
Genetically induced adverse reaction to a A patient suffering from allergic
certain drug is caused by various enzyme rhinitis was prescribed ephedrine in
defects. Name this reaction: form of nasal drops. The patient has
A. Idiosyncrasy significantly benefited from nasal
B. Withdrawal syndrome instillation, and this stimulated him to
C. Steal syndrome use the drug every 2 hours. But under
D. Rebound effect these conditions the drug appeared to
E. Dysbiosis be ineffective. What is the most likely
cause of this phenomenon?
A. Tachyphylaxis
B. Drug dependence
C. Idiosyncrasy
D. Allergy
E. Cumulation
A patient has been receiving palliative For thrombosis treatment a patient
treatment with morphine hydrochloride for a was prescribed a drug from the
week. Following that the patient demands group of direct anticoagulants.
continuation of this treatment. What What drug is it?
phenomenon has occurred in this A.Heparin
case? B. Fenilin (phenylinum)
A. Dependence C. Syncumar
B. Tolerance D.Neodicumarin
C. Cumulation E. Vikasol
D. Potentiation
E. Summation
Rifampicin is a cytochrome P450 inducer; A patient, who has been taking
therefore, its interaction with other acetylsalicylic acid, has developed
chemically active drugs: hemorrhages of mucous membranes.
A. Can decrease concentration of This phenomenon is associated with:
other drugs A. Inhibition of prothrombin
B. Can increase concentration of other synthesis
drugs B. Increased absorption in
C. Has no effect on concentration of gastrointestinal tract
other drugs C. Decreased absorption in
D. Can result in binding with other gastrointestinal tract
metabolites D. Disorder of protein binding
E. Has no effect on toxicity of other E. Changed volume of
drugs distribution
A patient with moderately severe An internship doctor prescribed his
pneumonia has been administered patient nifuroxazid from the group of
ceftriaxone 1 time per day. The drug nitrofurans for the treatment of urinary
should be taken once a day due to its tracts infection. The doctor made a
following property: mistake because:
A. Slow excretion A. It cannot be absorbed from the
B. Presence of bactericidal action digestive tract6
C. Wide range of action B. It is excreted with urine in the
D. Cumulative ability inactive state
E. Poor absorption from the injection C. It has nephrotoxic effect
site D. It has bacteriostatic effect
E. It is excreted from the organism
very slowly
A patient being treated in the infectious disease Absorption of tetracycline
ward for dysentery is administered phthalazol. preparations will be reduced when
What is the reason for phthalazol being used they are administered
only for treatment of enteric infections? simultaneously with antacids. This
A. The drug is not absorbed from the is an example for:
gastrointestinal tract A. Pharmacokinetic
B. The high degree of reabsorption in the incompatibility
kidneys B. Pharmaceutical incompatibility
C. Slowly eliminated from the body C. Pharmacodynamic
D. Rapidly absorbed in the gastrointestinal incompatibility
tract D. Drugs synergism
E. Rapidly excreted in unchanged form E. Functional drugs antagonism
A patient was prescribed an oral antibiotic for Advise an internship doctor on why
treatment and an antacid to remove heartburn iron preparations should not be
symptoms. If the drugs are taken administered together with antacids:
simultaneously their interaction can result in A. This causes malabsorption of
the following: iron
A. Antibiotic malabsorption B. This causes increased binding to
B. Relative overdosage blood proteins
C. Inhibition of hepatic microsomal C. This prevents deposition of iron
enzymes in the body
D. Mutual potentiation D. This increases intoxication with
E. Acceleration of metabolism and iron preparations
excretion E. This accelerates elimination of
iron preparations
When dispensing an antacid and ofloxacin in A patient suffering from epilepsy has
tablets, the dispensing chemist warned the taken phenobarbital for a long time
customer that these drugs should be taken and developed drug tolerance. What is
separately with 2- hour interval in between. the mechanism of this phenomenon
Simultaneous taking of both drugs: development?
A. Decreases ofloxacin absorption A. Acceleration of
B. Increases ofloxacin absorption biotransformation
C. Increases antacid effectiveness B. Absorption process reduction
D. Decreases antacid effectiveness C. Receptor’s sensitivity
E. Increases risk of dysbiosis enhancement
D. Inhibition of biotransformation
E. Accumulation of substances in
the body
In case of simultaneous use of Simultaneous use of doxycycline
metronidazole and oral anti-coagulants hydrochloride and oral contraceptive7
derived from coumarin patients must be causes:
warned about: A. Reduction of oral
A. Potentiation of anticoagulants contraceptives effectiveness
effect and risk of bleeding B. Increase of oral contraceptives
B. Reduction of anticoagulants effect effectiveness
C. Potentiation of metronidazole C. Increase of antibacterial effect
effect of doxycycline
D. Reduction of metronidazole effect D. Reduction of antibacterial
E. Higher neurotoxicity effect of doxycycline
Simultaneous use of gentamicin and Simultaneous use of paracetamol and
acyclovir tablets increases the risk of: acetylcysteine causes:
A. Nephrotoxicity A. Reduction of paracetamol
B. Hepatotoxicity hepatotoxicity
C. Cardiotoxicity B. Reduction of anti-inflammatory
D. Neurotoxicity action of paracetamol
E. Allergic reactions C. Inhibition of paracetamol
absorption
D. Increase of mucolytic action of
acetylcysteine
E. Increase of paracetamol
nephrotoxicity
A patient who has taken phenobarbital for A patient suffering from moderately
a long time was prescribed diclofenac severe pneumonia was prescribed
sodium. However the anti-inflammatory ceftriaxonum once a day. Prescription
effect of diclofenac appeared to be less of ceftriaxonum once a day is due to
than expected due to the pharmacokinetic the fact that the drug:
interaction of these drugs. Such A. Is slowly eliminated from the
interaction might be the result of the body
following processes: B. Has bactericidal
A. Accelerated drug metabolism in effect
liver C. Is
B. Decelerated drug metabolism in pluripotential
liver D. Accumulates in the
C. Reduced protein concentration in lungs
plasma E. Is poorly absorbed from
D. Change of receptor sensibility the injection site
E. Increased drug dosage
Name the reason for the reduction of A 25-year-old woman is in the third
anticoagulant effect of syncumar when it is trimester of her pregnancy. During her
applied in combination with phenobarbital: regular examination, US detected a
A. Phenobarbital activates microsomal malformation in the fetus. Medical history
liver enzymes of the patient shows that she was taking
B. Phenobarbital inhibits microsomal liver large doses of diazepam without
enzymes prescription during her pregnancy. What
C. Development of syncumar allergy type of side effect has occurred in this
D. These drugs are antagonists case?8
E. Mutual inactivation A. Teratogenic
B. Embryotoxic
C. Fetotoxic
D. Carcinogenic
E. Mutagenic
Benzathine benzylpenicillin is the drug of choice
for treatment of the following disease:
A. Syphilis
B. Intestinalinfection
C. Pneumonia
D. Tonsillitis
E. Furunculosis
Clinical Pharmacy in Cardiology
A patient after acute myocardial infarction A patient, who had a case of cardiac
has been recommended to take infarction, is recommended to take
acetylsalicylic acid for 3-4 months. What acetylsalicylic acid to:
effect of acetylsalicylic acid would be most A. Decrease thrombocyte aggregation
relevant for this patient? B. Decrease body temperature
A. Antiplatelet C. Dilate coronary vessels
B. Antipyretic D. Decrease inflammation
C. Analgesic E. Lower cholesterol rate
D. Antiinflammatory
E. Spasmolytic
A 60-year-old patient, who had suffered a A 52-year-old patient had myocardial
myocardial infarction, was prescribed infarction and was discharged from the
acetylsalicylic acid as an antiaggregant. hospital after the stationery treatment.
Specify the optimal daily dosage of What daily dose of acetylsalicylic acid
acetylsalicylic acid for antiaggregatory effect: should be administered in order to
A. 100 mg prevent thrombosis?
B. 200 mg A. 100 mg
C. 300 mg B. 500 mg
D. 400 mg C. 1000 mg
E. 500 mg D. 200 mg
E. 50 mg
A dispensing chemist was addressed by a A patient with myocardial infarction
patient with the prescription of has been given an intravenous
acetylsalicylic acid as antiaggregant. What injection of a direct-acting
daily dosage in grams should be anticoagulant. Select it among the
recommended for him to take on a regular listed drugs:
basis? A. Heparin
A. 0,1 – 0,3 B. Neodicumarinum
B. 0,5-1,0 C. Vikasolum
C. 1,0-2,0 D. Thrombin9
D. 2,0-3,0 E. Calcium gluconate
E. Over 4,0
Which drug is used for thrombolysis in case Which of the drugs listed below is used
of acute myocardial infarction? for thrombolytic therapy of myocardial
A. Alteplase infarction?
B. Acetylsalicylic acid A. Streptokinase
C. Heparin B. Heparinum
D. Pentoxifylline C. Рhenylinum
E. Fraxiparine D. Ticlopidine
E. Acetylsalicylic acid
A 46-year-old patient is diagnosed A patient suffering from essential
with cardiac infarction. What drug hypertension has increased concentration
should be prescribed for thrombolytic of renin in blood plasma. Which
therapy? pharmacological group should be
A. Streptokinase preferred for this patient treatment?
B. Nitroglycerine A. ACE inhibitors
C. Spironolactone (Verospiron) B. α-adrenoblockers
D. Drotaverine hydrochloride C. Diuretics
E. Trimeperidine (Promedol) D. Blockers of calcium channels
E. Sympatholytics
A patient with a history of essential A 24-year-old patient has been suffering for
hypertension has been administered diabetes mellitus type I for 8 years. Diabetic
lisinopril. What is the mechanism of action nephropathy provoked development of
of this drug? symptomatic arterial hypertension. Which of
A. It inhibits ACE the folowing drugs is indicated for long-term
B. It inhibits alpha-adrenergic receptors therapy?
C. It inhibits beta-adrenergic receptors A. Enalapril
D. It stimulates beta-adrenergic B. Propranolol
receptors C. Clonidine
E. It inhibits M-cholinergic receptors D. Dibazol
E. Dichlothiazide
What hypotensive drug is an agent of choice for A patient with hypertension has been
the patients suffering from arterial hypertension administered one of antihypertensive
with concomitant type I diabetes mellitus? drugs. Blood pressure dropped back to
A. Lisinopril normal, but the patient has developed a
B. Hydrochlorothiazide persistent dry cough. Which of the
C. Atenolol following drugs has such a side effect?
D. Labetalol A. Enalapril maleate
E. Carvedilol B. Propranolol
C. Clonidine
D. Furosemide
E. Nifedipine
A patient was warned that taking the A patient suffering from hypertension
prescribed preparation might cause cough. consulted a doctor about dry cough that
What drug is it? was presumably provoked by10
A. Lisinopril antihypertensive therapy. What
B. Clonidine antihypertensive drug had she been
C. Phenihidine taking?
D. Dichlothiazide A. Lisinopril
E. Metoprolol B. Аtеnоlоl
C. Nifedipinе
D. Furosemidum
E. Hydrochlorthiazide
A patient with essential hypertension complains A patient who has been treated for
of infrequent occurrences of dry cough. Clinical hypertension complains of cough.
and X-ray examination of the respiratory organs Objective examination reveals no
revealed no pathologies. What drug from those changes in the lungs. Which of the
taken by the patient can cause cough as a side following drugs might have caused
effect? cough?
A. Captopril A. Captopril
B. Diltiazem B. Amlodipine
C. Hydrochlorothiazide C. Hypothiazide
D. Nebivolol D. Nebivolol
E. Prestarium (Perindopril) E. Clonidine
A patient developed dry cough while A hypertensive patient has been
undergoing pharmacotherapy for arterial administered lisinopril. What side
hypertension. What group of drugs can be effect is typical for this drug?
characterized by this side effect? A. Dry cough
A. ACE inhibitors B. Constipation
B. Calcium antagonists C. Increased appetite
C. Antipsychotics D. Insomnia
D. Tranquilizers E. Vomiting
E. Antacids
A hypertensive patient has been A patient with arterial hypertension and
administered lisinopril. What side effect is chronic bronchitis suddenly developed
typical for this drug? dry cough and dyspnea; his body
A. Dry cough temperature remained without changes.
B. Constipation It is known that the patient takes
C. Increased appetite captopril. This phenomenon can be
D. Insomnia explained by increased synthesis of:
E. Vomiting A. Bradykinin
B. Angiotensin I
C. Renin
D. Aldosterone
E. Natriuretic peptide
A patient suffering from arterial hypertension A 56-year-old patient suffering from
and chronic bronchitis suddenly presented with essential hypertension was prescribed an
dry cough and dyspnea. Body temperature inhibitor of angiotensin converting enzyme
remained unchanged. It is known that the (ACE) and a potassium-sparing diuretic.
patient takes captopril. These symptoms can be Such combination is:
explained by increased generation of: A. Unreasonable because it increases11
A. Bradyquinine risk of hyperkaliemia development
B. Angiotensin-1 B. Reasonable because it decreases risk
C. Renin of hyperkaliemia development
D. Aldosterone C. Reasonable because it potentiates
E. Natriuretic peptide hypotensive effect of ACE inhibitor
D. Unreasonable because it reduces
hypotensive effect of ACE inhibitor
E. Unreasonable because it increases
risk of orthostatic collapse
development
Losartan as a part of treatment of arterial A pregnant woman complains of elevated
hypertension is contraindicated in case of: blood pressure up to 160/100. What
A. Pregnancy hypotensive drug should she use in this
B. Hyperglycemia case?
C. Urine acid diathesis A. Methyldopa
D. Hyperlipidemia B. Reserpine
E. Hypokalemia C. Enalapril
D. Losartan
E. Bisoprolol
A patient with hypertension was administered A 54-year-old hypertonic patient undergoing
metoprolol for the arterial pressure reduction. pharmacotherapy developed bronchial
What is its mechanism of action? spasm. His physician considers it to be a
A. Beta adrenoreceptor blockade therapy-induced complication caused by the
B. Alpha adrenoceptor blockade drug that belongs to the following group:
C. Indirect adrenomimetic action A. β-adrenergic blockers
D. Antispasmodic B. Calcium antagonists
E. Angiotensinic receptors blockade C. α-adrenergic blockers
D. Ganglionic blockers
E. Diuretics
A 52-year-old patient complains of having Which of the listed pharmacolgical
increased arterial pressure for a month. She has groups of antihypertensive drugs is
a 5-year history of bronchial asthma. What contraindicated the patients with
group of hypotensive drugs should NOT be bronchial asthma?
recommended this patient? A. Beta-adrenergic blocking
A. β-adrenoreceptor blockers agent
B. Calcium channel blockers B. ACE inhibitor
C. Tranquilizers C. Calcium channel blockers
D. Angiotensin receptor blockers D. Angiotensin receptors blockers
E. Diuretics E. Diuretics
A 60-year-old patient has essential A patient suffering from bronchial
hypertension stage II, coronary disease, asthma was diagnosed with essential
bronchial asthma. After pharmacotherapy hypertension. What antihypertensive
correction the patient exhibited a drug is contraindicated for this patient?
bronchospastic attack, intensified dyspnea. A. Propranolol
What drug provoked this complication? B. Captopril
A. Propranolol C. Amlodipine12
B. Nifedipinе D. Hypothiazid
C. Еuphyllinum (Hydrochlorothiazide)
D. Мucaltinum E. Verapamil
E. Salbutamolum
Recommend a drug for the treatment A 35-year-old patient with tachycardia
of tachyarrhythmia episodes: has been administered propranolol.
A. Propranolol Which of the following reactions may be
B. Adrenaline caused by the use of beta-blockers?
C. Atropine A. Bronchospasm
D. Caffeine sodium benzoate B. Drug dependence
E. Dobutamine C. Cumulation
D. Blood pressure rise
E. Constipations
What drug may cause the development of What drug may cause the development of
constipation in patients undergoing constipation in patients undergoing
combined therapy for arterial combined therapy for arterial
hypertension? hypertension?
A. Verapamil A. Verapamil
B. Furosemide B. Furosemide
C. Trimetazidine C. Trimetazidine
D. Pananginum D. Pananginum
E. Acetylsalicylic acid in small doses E. Acetylsalicylic acid in small doses
A 48-year-old woman addressed a dispensing A 70-year-old patient consulted a doctor
chemist with complaints of constipations about elevated arterial pressure. He has a
developing after she had started treatment of her history of benign hyperplasia of prostate.
chronic cardiovascular disease. What drug can What drug should be administered in this
slow down intestinal peristalsis? case?
A. Verapamil A. Doxazosin
B. Folicacid B. Еnаlаpril
C. Losartan C. Propranolol
D. Ascorbic acid D. Diltiazem
E. Enalapril E. Losartan
A pharmacy customer complains of A pharmacy customer complains of
constricting, sometimes burning pain behind constricting retrosternal pain that irradiates
the sternum, with irradiation to the neck and into the left arm; he fears that he may die.
left arm. The pain lasts for 5-10 minutes. The pain appeared suddenly after physical
What drug should be given to this customer exertion. Name the first aid medicine in this
for emergency aid? case:
A. Nitroglycerine A. Nitroglycerine
B. Bisoprolol B. Metacycline
C. Digoxin C. Naphthyzin (Naphazoline)
D. Isosorbide dinitrate D. Panangin
E. Nifedipine E. Riboxin (Inosine)
A 53-year-old woman suffers from ischemic After an emotional stress a 60-year-old
heart disease and angina pectoris. What drug patient presented with chest pain
can be used to stop angina pectoris attacks? irradiating to the left arm. Specify a drug13
A. Nitroglycerine that relieves pain in this case:
B. Drotaverine hydrochloride A. Nitroglycerine
C. Propranolol B. Nifedipine
D. Dipiridamol C. Diltiazem
E. Acetylsalicylic acid D. Propranolol
E. Metoprolol
A patient, who is undergoing treatment for A 70-year-old patient with stenocardia
ischemic heart disease, after physical claims that the pharmacy sold him a
exertion felt an acute pain in the cardiac area. drug that relieved an attack of
What drug can be prescribed in this case for stenocardia but instead caused an acute
quick relief of the pain syndrome? bursting headache. What
A. Nitroglycerine antihypertensive drug is this side effect
B. Enalapril typical for?
C. Corglycon (convallaloxin) A. Nitrosorbidе
D. Prazosin B. Amlodipine
E. Captopril C. Nifedipine
D. Trimetazidine
E. Metoprolol
A woman suddenly developed an angina In order to arrest stenocardia attacks a
pectoris attack. To arrest the attack, she took patient takes nitroglycerin capsules. What
a medicine that caused her a severe is the rational way of the drug
headache, facial hyperemia, and tachycardia. introduction?
Such side effects are characteristic of the A. Sublingual
following group of drugs: B. Peroral
A. Nitrates C. Rectal
B. Beta-adrenergic antagonists D. Inhalation
C. Alpha-adrenergic agonists E. Hypodermic
D. Calcium channel blockers
E. Antispasmodics
A patient with angina pectoris takes long- A patient with exertional angina pectoris had
acting nitrates. Consult him what side-effect is been taking isosorbide mononitrate orally
the most common for these drugs: for 2 months, when this drug lost its
A. Headache effectiveness. What is the likely cause of
B. Nausea isosorbidc mononitrate being no longer
C. Vomiting effective in this case?
D. Diarrhea A. Tolerance
E. Constipation B. Physical dependence
C. Cumulation
D. Psychological dependence
E. Sensitization
A patient has been taking isosorbide for A 45-year-old man has been taking long-
stenocardia prevention for quite a long acting nitrates twice a day for a year.
time. Now he notes a significant decrease Currently the decrease in effectiveness of
in the effect of the drug. What is this the pharmacotherapy is being observed.
phenomenon called? What side-effect can be suspected in the first
A. Tolerance place?14
B. Cumulation A. Development of nitrate tolerance
C. Physical dependence B. Progressing ischemic heart disease
D. Allergy C. Progressing coronary atherosclerosis
E. Potentiation D. Myocardial infarction
E. Impairment of coronary circulation
6 months after treatment a patient with A 63-year-old man suffering from ischemic
coronary heart disease developed tolerance heart disease was diagnosed with angle
to the prolonged-action nitrates. What drug closure glaucoma. What group of drugs is
with nitrate-similar effect should be CONTRAINDICATED in this case?
recommended in this case? A. Nitrates
A. Molsidomine B. β-adrenergic blockers
B. Nifedipine C. Calcium antagonists
C. Prazosin D. Anticoagulants
D. Verapamil E. Statins
E. Metoprolol
A patient with arterial hypertension, who takes A hypertensive patient had been
captopril, was prescribed a potassium-sparing administered a diuretic as a part of the
diuretic, spironolactone. What complication combined therapy. The administered
can develop in the patient due to this drug caused hypokalemia. Specify this
combination of drugs? drug:
A. Hyperkalemia A. Hydrochlorothiazide
B. Hypocalcemia B. Amiloride
C. Hyponatremia C. Spironolactone
D. Hypoglycemia D. Allopurinol
E. Hypernatremia E. Triamterene
A patient with ischemic heart disease and Select a loop diuretic of strong,
chronic circulatory failure had been taking emergency and short-term action from
for a long time one of the drugs listed the listed below:
below. He developed hypokalemia, which A. Furosemide
resulted in cardiac rhythm disturbance and B. Clopamide
muscle weakness. What drug can lead to C. Acetazolamide
this complication as a side effect? D. Spironolactone
A. Furosemide E. Triamterene
B. Lisinopril
C. Propranolol
D. Nifedipine
E. Spironolactone
A patient with heart failure has developed A 35-year-old patient has been
an electrolyte imbalance against the prescribed a potassium-sparing diuretic.
background of diuretic treatment with Select one such drug from the list:
furosemide. What imbalance has the A. Triamterene
patient developed? B. Prazosin
A. Hypokalemia C. Bisoprolol
B. Hypocalcemia D. Furosemide
C. Hyperkalemia E. Diltiazem
D. Hypermagnesemia15
E. Hypernatremia
Which of the following anti-hypertensive Treatment course of essential
drugs has potassium-sparing action? hypertension includes diuretics. Which
A. Triamterene diuretic DOES NOT NEED to be
B. Furosemide combined with potassium preparations?
C. Prazosin A. Triamteren
D. Metoprolol B. Clopamide
E. Diltiazem C. Dichlothiazide
D. Furosemide
E. Ethacrynic acid
A 68-year-old female patient has been A 67-year-old patient with chronic
continuously taking furosemide for heart heart failure takes digoxin. In order to
failure treatment. What drug should be reduce its side effects the patient’s
used to prevent hypokalemia in patients doctor recommended to combine it with
taking furosemide? the followig drug:
A. Panangin A. Panangin
B. Atp-long B. Calcium gluconate
C. Mildronatum C. Euphyllinum
D. Trimetazidine D. Hydrochlorthiazide
E. Sustac forte E. Calcium chloride
A 59-year-old patient has been using A 68-year-old man has been prescribed a
furosemide for a long time to treat his cardiac hypolipidemic agent as a part of his
insufficiency. What drug for hypokalemia combination therapy for ischemic heart
prevention should be used in the given case? disease. Name this drug:
A. Panangin (Potassium aspartate and A. Atorvastatin
magnesium aspartate) B. Nitroglycerine
B. Thiotriazolinum C. Lisinopril
C. Acetylsalicylic acid D. Nifedipine
D. Trimetazidine E. Hydrochlorothiazide
E. Enalapril
A patient with atherosclerosis has been A 65-year-old male patient complains of
administered an anti-atherosclerotic agent. nausea, vomiting, lethargy, seeing
Specify this drug: yellow spots in front of his eyes. The
A. Phenofibrate patient takes daily 0,25 mg of digoxin,
B. Ascorbic acid 100 mg of aspecardum, 50 mg of
C. Pyracetam metoprolol. What pathological
D. Dexamethasone condition is this syndrome typical for?
E. Phenylbutazone A. Glycoside intoxication
B.Food poisoning
C.Withdrawal syndrome
D. Tachyphylaxis
E. Hypersensitivity reaction
A 43-year-old woman has come to a
pharmacy with complaints of sharp headache
in the occipital area, palpitations, «visual
snow» in her eyes, nausea; her BP is 180/11016 mm Hg. These symptoms correspond with: A. Hypertensic crisis B. Migraine attack C. Exertional angina pectoris attack D. Cervical osteochondrosis E. Acute conjunctivitis
17
Clinical Pharmacy in Pulmonology
A female patient with pneumonia has In course of pharmacotherapy of
been administered doxycycline bronchitis a patient was found to have
hydrochloride. This drug relates to the dyspeptic disorders, photodermatitis,
following group of antibiotics: liver dysfunction. Which of the
A. Tetracyclines prescribed drugs might have caused
B. Aminoglycosides these manifestations?
C. Macrolides A. Doxycyсlin
D. Cephalosporins B. Paracetamolum
E. Penicillins C. Ascorbic acid
D. Асеtуlсуsteinum
E. Codeine phosphate
Select the optimal antibacterial drug for the A 26-year-old patient was diagnosed with
treatment of mycoplasma pneumonia: community-acquired pneumonia
A. Rovamycin provoked by mycoplasma. Choose the
B. Gentamicin appropriate antimicrobial preparation for
C. Penicillin the patient treatment:
D. Ampicillin A. Rovamycine
E. Amoxiclav B. Amoxicillin
C. Gentamycinum
D. Веnzylpenicillinum
E. Amoksiklav
A pregnant woman fell ill with severe A female patient in the first trimester of
pneumonia. Which of these antimicrobials pregnancy has been diagnosed with
should be administered to this patient? acute pyelonephritis. What is the
A. Cefotaxime antibiotic drug of choice for treating this
B. Gentamicin sulfate patient?
C. Tetracycline hydrochloride A. Amoxicillin
D. Ofloxacin B. Norfloxacin
E. Biseptol C. Gentamicin
D. Chloramphenicol
E. Amikacin
A gravida in her 20th week of gestation A 6-year-old child with pneumonia had
got ill with pneumonia. What been administered an antibiotic. After
chemotherapeutical drug may be treatment the child lost the hearing
administered with no risk for the fetus (became deaf). What group of
development? antibiotics might have caused this
A. Веnzylpenicillinum complication?
B. Gentamycin A. Aminoglycosides
C. Sulfalenum B. Cephalosporins
D. Laevomycetinum C. Macrolides
E. Ofloxacinum D. Natural penicillins
E. Semi-synthetic penicillins
A patient, who has undergone treatment for A 65-year-old man with community-
community-acquired pneumonia, complains of acquired pneumonia was prescribed18
hearing impairment. What antibacterial drug antibiotic agent amikacin. It should be kept
could result in such a side-effect? in mind, that amikacin has the following
A. Gentamicin side-effect:
B. Amoxicillin/clavulanate A. Ototoxicity
C. Cefazolin B. Red coloring of urine
D. Ciprofloxacin C. Vomiting
E. Clarithromycin D. Increased blood pressure
E. Decreased blood pressure
A 63-year-old woman suffering from diabetic Treatment of a patient who has
nephropathy with functional disturbance of the developed an attack of bronchial asthma
kidneys needs etiotropic treatment for focal for the first time should be started with:
pneumonia. What drug is A. Inhalation of ß2-agonists
CONTRAINDICATED in this case? B. Inhalation of glucocorticosteroid
A. Aminoglycosides C. Agonists parenterally
B. Natural penicillins D. M-anticholinergic drugs
C. Synthetic penicillins E. H2-histamine blockers
D. Macrolides
E. Combined penicillins
A patient with bronchial asthma was Select a drug for the treatment of
prescribed salbutamol that has led to relief of bronchial asthma from the group of ß 2-
bronchospasm symptoms. This is associated agonists:
with stimulation of: A. Salbutamol
A. β2-adrenoreceptors B. Aminophylline
B. α1-adrenoreceptors C. Atrovent
C. Muscarinic cholinoreceptors D. Ketotifen
D. Acetylcholine synthesis E. Beclomethasone
E. β1-adrenoreceptors
A patient with bronchial asthma has been When fenoterolum for inhalations is not
administered a drug from the group of beta- available in a pharmacy, it can be
adrenergic agonists. Specify this drug: substituted by the following drug from
A. Salbutamol the group of bronchoselective beta-2-
B. Diazepam adrenomimetics:
C. Doxycycline hydrochloride A. Salbutamolum
D. Nitroglycerine B. Isadrinum
E. Digoxin C. Metacinum
D. Ephedrinum
E. Еuphyllinum
Bronchodilatory effect of short-acting ß2- A 40-year-old patient suffers from bronchial
adrenoceptor agonist salbutamol develops asthma and cardiac rhythm disturbance in
after: form of bradyarrhythmia. Drugs of which
A. 5-10 minutes pharmacological group should be
B. 20-30 minutes administered for bronchospasm elimination?
C. 45-60 minutes A. Muscarinic receptor blockers
D. 2-3 hours B. Beta-adrenoceptor blockers
E. 4-6 hours C. Muscarinic cholinomimetics
D. Anticholinesterase drugs19
E. Muscle relaxants
A 40-year-old patient has a history of A 67-year-old patient who undergoes
bronchial asthma and heart rhythm treatment for bronchial asthma presents with
disorders in form of bradyarrhythmia. limb tremor, headache, insomnia,
Bronchospasm can be eliminated by the extrasystole. What drug might have caused
drugs of the following pharmacological such symptoms?
group: A. Theophylline
A. M-cholinergic antagonists B. Prednisolone
B. ß-blockers C. Tavegyl
C. M-cholinomimetics D. Intal
D. Cholinesterase inhibitors E. Acetylcysteine
E. Muscle relaxants
During an asphyxiating attack the patient with A patient has a history of chronic
bronchial asthma was given intravenously a bronchitis. Recommend him an
drug that caused nausea, headache, excitation, expectorant which can be purchased at
and palpitations as side effects. What drug can a pharmacy to facilitate the
cause such reaction? expectoration of thick and viscous
A. Euphylline (Aminophylline) mucus:
B. Prednisolone A. Ambroxol
C. Ambroxol B. Falimint
D. Suprastin (Chloropyramine) C. Glauvent
E. Papaverine hydrochloride D. Libexin
E. Salbutamol
A 5-year-old boy suffering from pneumonia has A 46-year-old pharmacy customer suffers
problems with mucus expectoration. A doctor from chronic bronchitis and needs a
prescribed him a mucolytic drug that stimulates medicine to facilitate expectoration of thick
surfactant synthesis. Name this drug: viscous sputum. What drug is indicated in
A. Ambroxol this case?
B. Carbocisteine A. Ambroxol
C. Mucaltin B. Oxeladin
D. Acetylcysteine C. Salbutamol
E. Potassium iodide D. Butamirate
E. Codeine phosphate
A 45-year-old man complains of wet cough. He Recommend a patient with acute
has been suffering from chronic bronchitis for bronchitis a mucolytic drug that
20 years. The patient is a smoker. He needs a facilitates expectoration:
mucolytic agent that will facilitate A. Acetylcysteine
expectoration and production of surfactant. B. Glaucine
What drug can be recommended to the patient C. Loratadine
in this case? D. Diclofenac sodium
A. Ambroxol E. Drotaverine hydrochloride
B. Thermopsis preparations
C. Licorice root
D. Proteolytic enzymes
E. Potassium iodide20
A 24-year-old man suffers from exacerbation of What pharmacological group of drugs
chronic bronchitis. This condition is CANNOT be combined with
accompanied by production of a small amount expectorants?
of viscous sputum. What drug is indicated to A. Antitussive drugs
facilitate the expectoration in this case? B. Decongestants
A. Acetylcysteine C. Polyvitamins
B. Oxeladin D. Antibacterial drugs
C. Fenoterol E. Mucolytic agents
D. Ipratropium bromide
E. Budesonide
A 46-year-old man came to a dispensing A patient, who has been taking an
chemist complaining of a dry cough. What expectorant, has developed complaints
antitussive drug can he be recommended? of hypersalivation, rhinitis, and itching
A. Oxeladin skin rashes (signs of iodism). What
B. Sodium bicarbonate medicine can cause these side effects?
C. Tripsin A. Potassium iodide
D. Acetylcysteine B. Mucaltin
E. Bromhexine C. Infusion of Thermopsis grass
D. Ammonium chloride
E. Ambroxol syrup
Which of the following drugs should be A patient with chronic bronchitis gets
used for prevention of bronchial asthma glaucine hydrochloride at a pharmacy.
attacks? The patient must be warned about the
A. Cromolyn sodium following typical side effect of this drug:
B. Salbutamol A. Arterial pressure drop
C. Drotaverine B. Excitation of the central nervous
D. Diphenhydramine hydrochloride system
E. Ambroxol C. Irregular heartbeat
D. Increased intraocular pressure
E. Allergic skin rash
Clinical Pharmacy in Rheumatology
A 33-year-old woman who has been Examination of a patient who has been
treated for chronic polyarthritis for a long treated for rheumatoid arthritis for a
time complains about arterial pressure long time revealed hyperglycemia.
rise, change of adipose tissue distribution, What drug might have caused it?
menstrual cycle disorder. What A. Dexamethasone
preparation has she taken? B. Diclofenac sodium
A. Prednisolone C. Ibuprofen
B. Indometacin D. Chloroquine
C. Butadion E. Levamisole
D. Synaflan
E. Diclofenac sodium
A 43-year-old patient with a severe A 52-year-old patient has been diagnosed21
form of rheumatoid arthritis has been with gouty arthritis, phase 2. What drug
administered a certain drug for should be basic in treatment of this patient?
background therapy. Specify this drug: A. Allopurinol
A. Methotrexate B. Hydrochlorothiazide
B. Diclofenac sodium C. Paracetamol
C. Nimesulide D. Furosemide
D. Prednisolone E. Penicillin
E. Methylprednisolone
A 34-year-old patient suffering from systemic It is necessary to prescribe non-steroid
lupus erythematosus takes methylprednisolone. anti-inflammatory drug for patient with
On examination the patient’s blood calcium is rheumatoid arthritis and concomitant
revealed to below. A doctor suspects duodenal ulcer. Which drug is the drug of
osteoporosis development. It is necessary to choice in this case?
prescribe the patient calcium preparations and: A. Celecoxib
A. Vitamin D3 B. Acetylsalicylic acid
B. B-group vitamins C. Paracetamol
C. Vitamin C D. Analgin
D. Vitamin A E. Diclofenac sodium
E. Vitamin E
A 57-year-old patient is diagnosed with Help the doctor to select a drug from
rheumatoid arthritis. Anamnesis states the group of non-steroidal anti-
peptic ulcer disease. What nonsteroidal inflammatory drugs, which is an
anti-inflammatory drug can be inhibitor of COX-2 and does not
recommended for this patient? damage the stomach:
A. Celecoxib A. Celecoxib
B. Diclofenac B. Acetylsalicylic acid
C. Aspirin C. Indomethacin
D. Indometacin D. Paracetamol
E. Mefenamic acid E. Diclofenac sodium
Which anaesthetic, anti-inflammatory, the A patient with osteoarthritis
least harmful for the stomach (gonarthrosis) and peptic gastric ulcer
preparation can be recommended to a in anamnesis must be prescribed a
patient with exacerbation of NSAID (nonsteroidal
rheumatoid arthritis? antiinflammatory drug). What drug
A. Celecoxib would be the most safe for this patient?
B. Diclofenac sodium A. Meloxicam
C. Acetylsalicylic acid B. Acetylsalicylic acid
D. Ibuprofenum C. Ibuprofen
E. Indometacinum D. Indometacin
E. Metamizole sodium
A pharmacy received a newgeneration Which of the following nonsteroid anti-
nonsteroid anti-inflammatory drug inflammatory agents has the least
"meloxicam" that mainly blocks harmful effect on mucosa of
cyclooxygenase-2. What advantages does gastrointestinal tract?
this preparation have in comparison with A. Nimesulide
other nonsteroid anti-inflammatory drugs? B. Diclofenac22 A. Minimal side effect on alimentary C. Indomethacin tract D. Piroxicam B. Evident myospasmolytic action E. Acetylsalicylic acid C. Interferonogenic properties D. Minimal side effect on hematogenesis E. Significant inhibition of protease activity
23
Clinical Pharmacy in Gastroenterology
A 20-year-old man suffers from chronic A patient suffering from stomach ulcer
hyperacid type B gastritis. Choose the was prescribed an antiulcer drug that also
antisecretory agent. reduces secretion of hydrochloric acid and
A. Omeprazole inhibits Chelicobacter pylori. What drug
B. Drotaverine hydrochlorid is it?
C. Clarithromycin A. Omeprazole
D. Levofloxacin B. Gastrocepine
E. Metoclopramide C. Maalox
D. Famotidine
E. Almagel
A 44-year-old man was diagnosed with During anti-Helicobacter quadrotherapy
chronic hyperacid gastritis. What patient’s feces colored black. What drug
pharmacological group of drugs would be could have caused this effect?
the most advisable in this case? A. Bismuth subcitrate
A. Proton pump inhibitors B. Omeprazole
B. Inhibitors of protein-degrading C. Amoxicillin
enzymes D. Clarithromycin
C. Beta-blockers E. Metronidazole
D. Glucocorticosteroids
E. Alpha-blockers
A man with gastric ulcer is prescribed anti- A patient with peptic ulcer disease has
Helicobacter pylori therapy. On the 3rd day developed black-colored feces during
the patient developed black coloring of feces. combined pharmacotherapy. Name the drug
What had caused such changes? that can be the cause of this development:
A. Bismuth subcitrate A. Bismuth subcitrate
B. Omeprazole B. Famotidine
C. Metronidazole C. Omeprazole
D. Tetracycline D. Lansoprazole
E. Tinidazole E. Ranitidine
In the course of clinical instrumental A patient suffering from stomach ulcer
examination a 45-year-old patient was was prescribed almagel. Which of its
diagnosed with chronic helicobacter- pharmacological properties is intended
associated type B gastritis. What group of for treatment of this pathology?
drugs should be prescribed first of all? A. HCl neutralization
A. Anti-Helicobacter pylori agents B. Local anaesthetization
B. Prokinetic agents C. Blocking the H2-histamine
C. Antacids receptors
D. Reparative drugs D. Blocking the muscarinic
E. Anti-Muscarinic cholinoreceptors
agents E. Anti-inflammatory action
A patient with cholelithiasis should be Several cholesterol gallstones are
administered the following drug for the detected in the gallbladder of a woman.
dissolution of cholesterol gallstones: Choose the drug to dissolve and excrete24
A. Ursodeoxycholic acid the stones:
B. Gamma-aminobutyric acid A. Ursodeoxycholic acid
C. Acetylsalicylic acid B. Papaverine
D. Citric acid C. Domperidone
E. Mefenamic acid D. Loperamide
E. Platyphyllin
A patient has a history of cholelithiasis. A patient has chronic pancreatitis with
What drug should be administered to apparent presentations of pancreatic
prevent biliary colic? exocrine hypofunction. Which of the
A. Magnesium sulfate following drugs would be the most
B. Almagel advisable in this case?
C. Contrycal A. Раncreatinum
D. Bisacodyl B. Drotaverine
E. Pancreatin C. Dе-Nоl
D. Оmерrаzоlе
E. Acidin pepsinum
Clinical Pharmacy in Hepatology
A man with a long history of chronic A man with a long history of chronic
hepatitis has been diagnosed with hepatitis has been diagnosed with
pneumonia. Which of the following pneumonia. Which of the following
antibacterial drugs can be applied in this antibacterial drugs can be applied in
clinical situation? this clinical situation?
A. Amoxicillin A. Amoxicillin
B. Tetracycline B. Tetracycline
C. Biseptol C. Biseptol
D. Rifampicin D. Rifampicin
E. Vancomycin E. Vancomycin
Clinical Pharmacy in Haematology
A 36-year-old patient complains of general A patient who has been suffering
weakness, somnolence, increased brittleness of from gastric diseases for a long time
nails, loss of hair. The patient was diagnosed is found to have hyperchromic
with iron-deficiency anemia. What drug should anemia. Which of the following
be prescribed for treatment? drugs is applied for this pathology
A. Ferric sulfate treatment?
B. Cyanocobalamin A.Сyanocobalamine
C. Folic acid B. Ascorbic acid
D. Myelosanum (Busulfan) C. Unitiol
E. Riboxin (Inosine) D.Ferrum Lek
E. Охуferriscorbone25
To treat iron-deficiency anemia the following
drug is usually prescribed:
A. Ferroplex
B. Furagin (Furazidinum)
C. Corticosteroids
D. Heparin
E. Vicasol (Menadione)
Clinical Pharmacy in Nephrology
A 25-year-old man is diagnosed with acute A female patient in the first trimester of
pyelonephritis of moderate severity. What pregnancy has been diagnosed with
drugs should be prescribed for etiotropic acute pyelonephritis. What is the
therapy? antibiotic drug of choice for treating this
A. Antimicrobial agents patient?
B. Glucocorticoids A. Amoxicillin
C. Nonsteroidal antiinflammatory B. Norfloxacin
drugs C. Gentamicin
D. Anticholinesterase drugs D. Chloramphenicol
E. Antiarrhythmic drugs E. Amikacin
A 28-year-old pregnant woman (8-9 What is the drug of choice for the
weeks) after clinical examination and treatment of acute pyelonephritis in a
laboratory analysis was diagnosed with pregnant woman in the I trimester?
acute pyelonephritis. What empiric A. Amoxicillin
antibacterial therapy will be optimal in this B. Norfloxacin
case? C. Biseptolum
A. Amoxicillin D. Gentamicin
B. Norfloxacin E. Chloramphenicol
C. Chloramphenicol
D. Gentamicin
E. Tetracycline
A 12 weeks pregnant patient has been A 43-year-old patient was brought into an
hospitalized with symptoms of acute admission room with renal colic attack. What
cystitis. What antibiotic can be group of drugs would be the most effective for
recommended in this case? attack relief?
A. Amoxicillin A. Antispasmodics
B. Ciprofloxacin B. Cholagogues
C. Gentamicin C. Antacids
D. Metronidazole D. Hepatoprotectors
E. Tetracycline E. Antibiotics
Exacerbation of urolithiasis has caused a Select a loop diuretic of strong,
renal colic in the patient. What drug must emergency and short-term action from
be administered to arrest the colic? the listed below:
A. Drotaverine hydrochloride A. Furosemide
B. Siliborum B. Clopamide
C. Almagel C. Acetazolamide
D. Aethimizolum D. Spironolactone26
E. Neostigmine methylsulfate E. Triamterene
Which of the following diuretics
SHOULD NOT be administered to
patients with impaired hearing?
A. Furosemide
B. Spironolactone
C. Clopamide
D. Indapamide
E. Chlorthalidone
Clinical Pharmacy in Endocrinology
A 15-year-old patient has been first A 17-year-old patient complains of
diagnosed with type I diabetes mellitus. persistent thirst, dry mouth, frequent
Which antihyperglycemic drug should be urination, increased appetite. Blood
administered in this case? glucose is at the rate of 11 mmol/l. The
A. Insulin patient has been diagnosed with diabetes
B. Metformin mellitus type I. What drug is indicated for
C. Diabetone treatment?
D. Glurenorm A. Insulin
E. Glibenclamide B. Maninil
C. Glibenclamide
D. Acarbose
E. Asparcamum
An 18-year-old girl was hospitalized with A 24-year-old patient after a thorough
complaints of polyuria, dry skin, loss of examination was diagnosed with type 1
weight, and general weakness. She was diabetes mellitus for the first time. What
diagnosed with diabetes mellitus type I, first antihyperglycemic agent should be
diagnosed. What drug should be taken first prescribed in this case?
in the course of the therapy? A. Insulin
A. Insulin B. Glibcnclamide
B. Exenatide C. Metformin
C. Metformin D. Etacrynic acid
D. Glibenclamid E. Urea
E. Arphasetin
A woman with diabetes mellitus has A woman with diabetes mellitus has injected
developed hypoglycemia after insulin herself with 30 units of insulin. After that she
overdose. What measures should be taken at developed weakness and acme to the
the first signs of hypoglycemia? pharmacy to ask for help. In the pharmacy
A. Give the patient a sugar lump to eat she lost her consciousness and developed
and a cup of warm sweetened tea convulsions. What should she be given
B. Introduce 0.1% adrenaline solution immediately?
subcutaneously A. Glucose
C. Give nitroglycerine sublingually B. Insulin
D. Make an insulin injection C. Glibenclamid27
E. Make an intramuscular injection of D. Butamide (Tolbutamide)
caffeine E. Metformin
What drug is used to treat A 48-year-old patient has undergone
hyperthyroidism? incomplete amputation of the thyroid gland.
A. Mercazolil (Thiamazole) Choose the drug for replacement therapy in
B. Oxytocin case of hypothyroidism:
C. Prednisolone A. L-thyroxin
D. Metformin B. Hydrocortisone
E. Insulin C. Insulin
D. Metoprolol
E. Prednisolone
Help the doctor to select a drug for the A female 49-year-old patient complains
replacement therapy after the thyroid of compressing headache in the occipital
gland removal: region, dizziness, increased AP. The
A. L-thyroxine patient has a history of diabetes mellitus
B. Insulin type II. What diuretic DOES NOT affect
C. Prednisolone the blood glucose level?
D. Parathyroidin A. Indapamide
E. Mercazolilum B. Furosemide
C. Hypothiazide
D. Ethacrynic acid
E. Urea
Which of the listed antibacterial drugs
should NOT be administered to a
patient with diabetes mellitus type II
being treated with glibenclamid?
A. Co-trimoxazolum
B. Midecamycin
C. Gentamycinum
D. Benzylpenicillinum
E. Doxycycline28
Clinical Pharmacy in Allergology
A patient had been given an injection of A patient after bee’s stings has
0,25% novocaine solution for the purpose angioedema (Quincke’s edema). Which
of anaesthetization. Suddenly the patient drug should be immediately inject to
developed red spots, intense sweating, eliminate this condition?
tachycardia, bronchospasm, edema of A. Epinephrine hydrochloride
nasal mucosa. What is the cause of this B. Sodium chloride
complication? C. Platyphyllini hydrotartras
A. Immediate allergy D. Atropine sulfate
B. Delayed allergy E. Аnарrilinum
C. Local irritation
D. Tachyphylaxis
E. Withdrawal syndrome (Abstinence
syndrome)
A patient is 20 years old. After she was A patient with atopic dermatitis
stung by a bee the patient developed presented to the hospital. Which drug
Quincke’s disease; rash in the form of with anti-inflammatory and antiallergic
blisters and papulae appeared on her effect should be administered to this
torso. First aid in this case should start patient?
with administering the following drug: A. Prednisolone
A. Prednisolone B. Aethamidum
B. Penicillin C. Oxytocin
C. Fresh frozen plasma D. Insulin
D. Rheopolyglukin (Dextran) E. Retabolilum
E. Haemodes
What drug should be used first in case of A bus driver addressed a pharmacy due to his
anaphylactic shock? suffering from allergic rhinitis. What
A. Prednisolone antihistamine with minimal sedative action
B. Dibazol (Bendazol) can you recommend?
C. Fexofenadine A. Loratadine
D. Euphyllin (Aminophylline) B. Clemastine
E. Loratadine C. Astemizole
D. Diphenhydramine
E. Chloropyramine29
Pharmaceutical Care
A 25-year-old patient with frequent One of the substances listed below
migraine attacks has been prescribed is NOT a vitamin:
sumatriptan. Specify the mechanism A. Calcium gluconate
of its action: B. Calcium pangamate
A. Selective agonist of 5−HT1- C. Calcium pantothenate
serotonin receptors D. Ergocalciferol
B. Selective antagonist of 5−HT1- E. Nicotinic acid
serotonin receptors
C. Nonselective ß-blocker
D. Stimulator of ß-adrenergic
receptors
E. Selective ß-blocker
A 60-year-old man has come to a pharmacy A 35-year-old female customer came to
with complaints of impaired twilight vision, a pharmacy to purchase a medicine for
dry sclera, cracked and peeling skin. The the prevention of influenza. Which of
dispensing chemist suspected hypovitaminosis the following drugs can be
and recommended the customer to take the recommended?
following drug after consultation with the A. Rimantadine
physician: B. Acyclovir
A. Retinol acetate C. Ribavirin
B. Tocopherol acetate D. Ganciclovir
C. Ergocalciferol E. Lamivudine
D. Vicasol (Menadione)
E. Ascorbic acid
A 36-year-old woman with herpetic rash on What topical antiviral agent should be
her lips has come to a pharmacy. Recommend recommended to the patient with herpetic
her a drug for topical treatment: lesions on the lips?
A. Acyclovir A. Acyclovir
B. Fluconazole B. Arbidol (Umifenovir)
C. Levofloxacin C. Amizon (Enisamium iodide)
D. Metronidazole D. Aflubin
E. Amikacin E. Anaferon
A patient with arterial hypertension was How long can vasoconstrictors for
administered a non-prescription drug for symptomatic treatment of rhinitis be
symptomatic treatment of rhinitis. What used?
pharmaceutical form should be recommended A. 5-7 days
the patient in order to reduce as much as B. 1 month
possible the likelihood of development of C. 2 weeks
undesirable systemic vasoconstriction? D. 3 weeks
A. Ointment E. 5 weeks
B. Gel
C. Drops
D. Aerosol
E. Tablets30
What is the most suitable drug that can be A pregnant woman with signs of acute
recommended for the treatment of rhinitis rhinitis came to a pharmacy. What drug
accompanying an ARVI in a 7-month-old for symptomatic treatment of rhinitis
child? will be the safest in this case?
A. 0,9% warm water solution of A. Salt solutions based on iso- and
NaCl hypotonic sodium chloride solutions
B. Naphthyzin B. Beclomethasone preparations
C. Galazolin C. Essential oil-based preparations
D. Pinosol D. Cromoglicic acid preparations
E. Boromentol ointment E. Xylometazoline preparations
A patient complaining of stuffy nose, A young mother has come to a pharmacy to
fatigability, and headache came to a buy an antipyretic drug for her 3-month-old
dispensing chemist. What medicine infant. What dosage form would you choose
should be recommended to treat stuffy for the infant?
nose in this case? A. Suppositories
A. Xylometazoline B. Tablets
B. Paracetamol C. Capsules
C. Dexamethasone D. Spray
D. Acyclovir E. Lozenges
E. Lactulose
A 3-year-old child is intolerant to paracetamol. A woman asked a pharmaceutist to
What antipyretic drug can be taken instead? dispense an antipyretic for an 8-
A. Ibuprofen month-old child. Which drug
B. Acetylsalicylic acid should be recommended?
C. Nimesulide A. Paracetamol
D. Naproxen B. Acetylsalicylic acid
E. Diclofenac sodium C. Indomethacin
D. Diclofenac sodium
E.Piroxicam
Mother of a 2-month-old child came to a What drug can be recommended for
pharmacy and asked for a febrifuge. What symptomatic treatment of muscle pain in a
drug should be recommended for the child? 5-year-old child?
A. Paracetamolum A. Paracetamol
B. Nimesulide B. Acetylsalicylic acid
C. Acetylsalicylic acid C. Diclofenac sodium
D. Indometacinum D. Indomethacin
E. Diclofenac sodium E. Celecoxib
A woman in the III trimester of pregnancy A 26-year-old pregnant woman (III
has an acute respiratory viral disease trimester of pregnancy) complains about
accompanied with body temperature rise up body temperature rise up to 39oC. What
o
to 39 C. Which of the drugs should be febrifuge may be recommended in this case?
recommended? A. Paracetamol
A. Paracetamol B. Aspirin
B. Celecoxib C. Diclofenac
C. Indomethacin D. Analgin
E. IndometacinYou can also read
