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Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Innovation
through HTA
VIRTUAL CONFERENCE BAG

                      June 19-23, 2021
                     www.htai2021.org
                   #HTAi2021VirtualAM
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Dear Delegates,

Welcome to the HTAi 2021 Virtual Annual Meeting!

Each year, HTAi Annual Meetings bring together over 1,000 researchers, policymakers, industry, academia, health
service providers, agencies, patients, and consumers from around the world. The meetings provide an arena for these
groups to share information and best practices, from cutting-edge technologies to system development in order to
advance healthcare.

This year’s meeting is the first large-scale, five-day virtual event from HTAi, and we are thrilled to have you join the
excitement! From the high-caliber and engaging content, to the top-notch entertainment and abundant networking
opportunities—the 2021 Annual Meeting will be an event to remember.

The HTAi Virtual Annual Meeting will officially kick off with the Welcome Reception on Sunday, June 20 at 15:00 (UTC).
Mark your calendars now so you don’t miss out on our notable guest speaker and exceptional entertainment.

The HTAi social media team will be fully engaged throughout the entire meeting, and they want to hear from you! Use
the hashtag #HTAi2021VirtualAM to engage with fellow delegates, share your best moments, pose questions, and
provide your thoughts on the presentations you attend; we love to see your learning moments and biggest takeaways. If
you’re on LinkedIn, you can also chat with attendees in the LinkedIn virtual meeting group.

Don’t forget to tag HTAi in your posts:

        Twitter: @HTAiOrg
        LinkedIn: @Health Technology Assessment international (HTAi)
        Facebook: @HTAiOrg
        Instagram: @htai_

HTAi would like to extend a hearty thank-you to all of our volunteers, sponsors, and local hosts for working hard to
ensure this meeting is a success. If you would like to show our teams your gratitude, spend some time in our virtual
exhibition hall and interacting with our on-demand content, available in the Annual Meeting portal.

Thank you for supporting the HTAi 2021 Virtual Annual Meeting. We can’t wait to see you there!

Sincerely,

The HTAi Annual Meeting Team
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
HTAi 2021 Virtual Annual Meeting

TUMOR-AGNOSTIC MEDICINES FOR RARE
GENOMIC ALTERATIONS: MEETING THE
HTA AND MARKET ACCESS CHALLENGES

In the era of precision medicine, there has been a shift from organ-based to tumor-
agnostic, anti-cancer platforms, based on the molecular driver of the tumor. The recent
regulatory approval of tumor-agnostic drugs for patients with rare tropomyosin receptor
kinase (TRK) fusion cancer signals the emergence of more novel therapies targeting
specific genomic alterations.

While experts agree that randomized clinical trials are not possible for such therapies, HTA
authorities prefer them for decision making. Is there a disconnect between conventional
HTA expectations and the scientific and medical attributes of tumor-agnostic therapies?
If so, what adaptations are needed to enable evidence-based access to these therapies?

Join our panelists to gain insight into the implications of tumor-agnostic medicines for HTA
and patient access and to learn about adapted evidence requirements, characterization of
patient outcomes and valuation of these therapies.

Learning Objectives

•      Understand the need to examine and redefine the pathway to market access for tumor-agnostic therapies

•      Explore how clinical trial design and data collection are increasingly oriented to regulatory requirements
       that have evolved and are supportive of novel mechanisms of action

•      Understand how patient needs and preferences can be included among the factors considered by HTA bodies
       when assessing the value of new treatments

•      Compare and evaluate HTA outcomes in different countries and explore the need for flexibility and advances
       in HTA processes to capture the value of tumor-agnostic therapies, including evolving evidence requirements

Monday, June 21st, 14:30 – 15:45 (UTC)                             VISIT HTAI.EVENTSAIR.COM/HTAI-MANCHESTER-2021-AM/SYMPOSIA

Job Code: MAC-VIT-ALL-0014-1                                                                                         Date of Preparation: May 2021
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
HTAi 2021 Virtual Annual Meeting

TUMOR-AGNOSTIC MEDICINES FOR RARE
GENOMIC ALTERATIONS: MEETING THE
HTA AND MARKET ACCESS CHALLENGES
Agenda

                    Clifford Goodman
                                                                                       Tumor-Agnostic Medicines:
                    Sr. Vice President, The Lewin Group                                the current access situation

                    Carsten Bokemeyer
                                                                                       Transformations in cancer treatment & the
                    Head of Oncology, Hematology, BMT & Director Cancer Center,
                                                                                       challenge of collecting evidence for HTA bodies
                    University Medical Center Hamburg-Eppendorf

                    Lydia Makaroff
                                                                                       Incorporating patient preferences
                    CEO of Fight Bladder Cancer, Vice President of the World Bladder
                                                                                       into access decision making
                    Cancer Patient Coalition

                    Andrew Briggs
                                                                                       Economic modeling to mitigate HTA challenges
                    Professor of Health Economics, Department of Health Services       when evaluating tumor-agnostic medicines –
                    Research & Policy, London School of Hygiene & Tropical Medicine    learnings from the UK

                    Gérard de Pouvourville
                                                                                       Access and reimbursement to tumor-agnostic
                    Emeritus Professor, ESSEC Business School                          medicines – learnings from France

Bayer is at the forefront of the evolving global oncology                         cancers, but a patient’s individual tumor based on the genomic
landscape. It is our aspiration to transform the lives of people                  alterations driving its growth, rather than its location in the
impacted by cancer through science and innovation. World-                         body. We encourage the initiation of genomic testing early after
leading research, pharmaceutical, advocacy and academic                           diagnosis, so that precision medicine can be considered earlier in
partners support us with this aspiration. Together, we are paving                 the treatment journey. Ultimately, our goal is to make a difference
the way in innovative science with an emphasis on delivering true                 in the lives of patients and their families undergoing their
precision medicine treating not only organ-based                                  cancer journey.

Monday, June 21st, 14:30 – 15:45 (UTC)                                    VISIT HTAI.EVENTSAIR.COM/HTAI-MANCHESTER-2021-AM/SYMPOSIA

Job Code: MAC-VIT-ALL-0014-1                                                                                                             Date of Preparation: May 2021
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Takeda
Creating better
health for people
and a brighter
future for the world

Takeda UK and Ireland

  We are Takeda,          Our purpose is simple:                     From our very beginning
  a world leader in       to create better                           in Japan in 1781, we
  gastroenterology,       health for people                          have been guided by
  rare disease and        and a brighter future                      our purpose. It inspires
  specialty care          for the world. In the UK                   everything we do and
  medicine.               that means putting                         enables us to act in
                          patients first.                            the best interests of
                                                    #1               society at
                                                                     all times.

 In the UK and Ireland,
                           “I am passionate about                     “At Takeda, patient-first
 we are 400 people         helping clinicians make a                  culture isn’t just a value, it’s
 who bring this            difference for their patients.”            a way of life.”
 purpose to                BERNADETTE SAUNDERS,                       KATY, SENIOR MEDICAL SCIENCE
 life through              NEUROSCIENCE ACCOUNT LEAD IN
                           ADHD ACROSS THE LIFESPAN
                                                                      LIAISON, IMMMUNOLOGY

 an unwavering
 commitment
 to putting
 the patient
 first.

  Driving innovation                   We currently          Through these collaborations, we accelerate the
  through partnerships               have 22 active          development of breakthrough scientific innovations
                                                             that can redefine the standard of patient care.
  and R&D                              partnerships
                                      with biotechs                        We have established LSHTM’s very
                                                                           first fully endowed corporate chair, the
                                     and academic                          Takeda Chair in Global Child Health. The
                                      institutions in                      Chair supports vital research to help
                                                                           reduce child deaths in low and middle-
                                        the UK and                         income countries.

    $1.3bn                                   Ireland.
                                                             Our partners include:
    In 2020, we agreed
    R&D partnerships
    in the UK worth a
    potential $1.3bn.

                                                                                       Job code: C-ANPROM/UK/CORP/0047
www.takeda.com/en-gb                                                                           Date of preparation: May 2021
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
OUR GLOBAL TEAM                           We focus on four therapeutic areas: oncology,
        ARE TRANSLATING SCIENCE                       gastroenterology (GI), rare diseases and neuroscience.
            INTO POTENTIALLY
        LIFE-CHANGING MEDICINES.                                 We also make targeted R&D investments in
                                                                 plasma-derived therapies and vaccines.

  Supporting patient organisations

  Our “I am number 17” campaign, together with           Our award-winning “In My Shoes” campaign
  13 patient groups, reached 16 million people           with Crohn’s & Colitis UK used an immersive app
  and helped to change public perceptions of             to help improve people’s understanding about
  rare diseases.                                         what it is like to live with Crohn’s or Colitis.

  Working closely           We work closely with the NHS to help
                            provide better care for patients and
                                                                           new community-based nurse service to
                                                                           support young people.
  with the NHS              increase access to potentially life-changing
                            healthcare services.
                                                                           We have also developed a mobile app with
                            We are supporting the development of the       local NHS services to better monitor the
                            Heart of England NHS Foundation Trust          effectiveness of treatment.
                            paediatric ADHD service, establishing a

                                                                                              Job code: C-ANPROM/UK/CORP/0047
www.takeda.com/en-gb                                                                                  Date of preparation: May 2021
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Health Technology Wales is a national
organisation supporting the innovation and
adoption of non-medicine technologies that will
improve health and care in Wales.
We focus on any health and care technologies that aren’t
medicines, such as:

   MEDICAL DEVICES       PSYCHOLOGICAL THERAPIES      REHABILITATION

     SURGICAL PROCEDURES       TELEMONITORING       CARE PATHWAYS

We work with people across the health and care landscape:

     NHS WALES       HEALTH & SOCIAL CARE PROFESSIONALS       PUBLIC

                 ACADEMICS         WELSH GOVERNMENT

          PATIENTS       TECHNOLOGY DEVELOPERS       CARERS
Innovation through HTA - VIRTUAL CONFERENCE BAG June 19-23, 2021 www.htai2021.org #HTAi2021VirtualAM
Our work focuses on three main areas:

   IDENTIFICATION              Responding to the needs of service users,
                               healthcare providers and technology developers
                               across Wales.
                               ‘Horizon scanning’ to identify upcoming
                               technologies that may have a major impact on
                               Wales in the future.
                               Signposting technology developers to
                               organisations that can give advice and support.

     IDENTIFICATION
      APPRAISAL                Producing appraisal reports that summarise
                               the available evidence on a health technology,
                               including input from experts.
                               Providing authoritative, evidence-based Guidance
                               to inform decision makers on whether they
                               should adopt a technology.
                               Building learning and skills in health technology
                               assessment, including the appraisal of clinical,
                               safety and economic evidence.

       APPRAISAL

      ADOPTION                 Monitoring the uptake of guidance across Wales.
                               This includes both our HTW Guidance and
                               guidance from the National Institute for Health
                               and Care Excellence.
                               Making recommendations on research priorities
                               to improve the available evidence.
                               Encouraging uptake of effective technologies,
                               and disinvestment in technologies that are no
                               longer effective.

       ADOPTION

Discover more
Web		             www.healthtechnology.wales
Telephone         +44 (0)29 2046 8947
Twitter		         twitter.com/HealthTechWales
LinkedIn          www.linkedin.com/company/healthtechnologywales/
NICE strategy 2021 to 2026
Dynamic, Collaborative, Excellent

Our transformation starts now. We’ve launched an ambitious new strategy, which
explains how we’re working more collaboratively than ever before. We’re sharing our
knowledge and expertise internationally and learning from other health systems, to
inform our work.

To find out more:
visit our virtual exhibition booth at the HTAi 2021 Virtual Annual Meeting
or go to www.nice.org.uk/strategy
NICE International
Working with you to improve global health outcomes

We are NICE International – part of the UK’s
National Institute for Health and Care Excellence
and closely connected to the National Health Service.
                                                                         “NICE was an affirming
                                                                         influence and an inspiring
We aim to help countries improve their nation’s
                                                                         force to improve our
health and wellbeing by sharing our knowledge and
experience of guideline development and health                           policies and practices
technology assessment.                                                   in transparency and
                                                                         accountability, including
We collaborate the world over to enable
health organisations, ministries and government                          how to have useful
agencies to:                                                             consultations with
                                                                         experts and patients,
    make better and more cost-effective
    health and care decisions                                            liaise with pharmaceutical
    allocate finite resources                                            companies and network
    improve care quality                                                 with academia.”
    reduce variation in access to care.
                                                                        Dr Marita Reyes
We’ll work with you to understand your questions,
                                                                        Chair of the HTA Council
challenges or ambitions and tailor our support                          of the Philippines
services to meet your needs.

To find out more visit
www.nice.org.uk/niceinternational                   © NICE 2021. All rights reserved. Subject to www.nice.org.uk/terms-and-conditions
Novartis-sponsored
symposium

                     Novartis sponsored symposium at the Health Technology
                     Assessment international Congress (HTAi 2021)

                     Converging novel HTA and access
                     pathways in adaptable healthcare systems
                     Tuesday 22 June 2021, 16:00–17:00 (CEST)
                     HTAi Annual Meeting Manchester UK, Virtual Meeting

                     Novartis is committed to reimagine medicine to transform healthcare systems (HCS) and improve
                     access to patient-populations in need. However, bringing newer technologies and 21st century
                     medicines to patients can challenge traditional funding thresholds and approaches.

                     The existing health technology assessment (HTA) frameworks can be limited in evaluating the
                     complexity of advances in HCS. The use of adaptive frameworks and disruptive launch models
                     may have the ability to address these needs. One of the key elements of adaptive HTAs should
                     therefore be the development of multi-stakeholder collaborative networks for innovations to
                     flourish and spread, thus accelerating countries’ progress on health-related priorities.

                     In our endeavor to bridge the gap between HCS/HTA and patient access, we have arranged a
                     symposium on “Converging novel HTA and access pathways in adaptable healthcare systems” at
                     the HTAi Annual Meeting Virtual Event 2021. We aim to understand through the eyes of the HTA/
                     payers, industry, and policy-makers, the key attributes and challenges between innovation and
                     recent HTA frameworks to accelerate access.

                     This satellite symposium is organized and funded by Novartis Pharma AG
                     © Novartis Pharma AG, 2021, CH-4002 Basel, Switzerland
                     May 2021
Novartis sponsored symposium at the Health Technology
Assessment international Congress (HTAi 2021)

Converging novel HTA and access
pathways in adaptable healthcare
systems
Tuesday 22 June 2021, 16:00–17:00 (CEST)
HTAi Annual Meeting Manchester UK, Virtual Meeting

Chair: Michele Mestrinaro, Switzerland

16:00              Welcome and introduction
                   Michele Mestrinaro
                   Global Head of Pricing and Access Policy, Novartis AG, Switzerland

                   Participant introductions and opening remarks
                   Prof. Zoltán Kaló
                   Professor of Health Economics at Center for HTA, Semmelweis University
                   Budapest, Hungary
                   Dr. Karen Facey
                   Evidence Based Health Policy Consultant, Scotland
                   Prof. Jinxi Ding
                   Professor and Vice Dean, School of International Pharmaceutical Business,
                   China Pharmaceutical University, China
                   Dr. Laurie Lambert
                   Real World Evidence Lead at Canadian Agency for Drugs and Technologies
                   in Health, Canada

16:10              Q&A – Moderated panel discussion
                   All Faculty

16:45              Q&A - Audience
                   All Faculty

16:55              Closing Remarks
                   Michele Mestrinaro

  For any questions related to the symposium, please contact:
  Dr. Judit Bánházi, Global HEOR Director, Novartis Pharma AG, Basel, Switzerland
       judit.banhazi@novartis.com |                       +41799375703

The symposium recording will also be available for on-demand viewing on the HTA Congress website, until September 2021.

This satellite symposium is organized and funded by Novartis Pharma AG
© Novartis Pharma AG, 2021, CH-4002 Basel, Switzerland
May 2021
ASERNIPS
We are global leaders in health technology
assessment. Our team of experts assess
technologies relevant to surgeons and the
surgical environment; and, we are uniquely
positioned within a Medical College providing us
access to clinicians. We will work closely with you
to identify your specific requirements and provide
individualized and highly insightful safety and
effectiveness assessments, statistical analyses
and health economic reviews.

Our services include:

      Surgical procedure assessments that review
      existing or emerging surgical practices to inform
      funding decisions.

      Medical device assessments of new and
      emerging devices to inform investment and
      approval decisions.

      Pathology test and diagnostic imaging reviews
      that assess validity and clinical utility and impact
      on patient management.

      Training services including the development and
      delivery of Health Technology Assessment training
      materials and research into Simulation-based
      education for surgery.

To discuss your technology assessment
needs please contact Dr David Tivey
at +61 410 451 663 or
racs.asernip@surgeons.org.

We look forward to meeting you during HTAi 2021.
Exploring the impact of patient voice
and its representation in the HTA
organization decision-making process

There has been concerted effort in recent years to further integrate the patient voice in HTA. The perspective
of the patient and their caregiver may differ from the HCP, and tends to elevate safety and tolerability of
treatment.1,2 These efforts are initiating or already underway around the globe, led by HTA, regulatory
agencies, and advocacy groups.3

          HTA organizations incorporating patient input in their assessments4:

                                                                             SMC (Scotland)

                                                                                              IQWIG
                                                                    NICE                      (Germany)
                                                                    (UK)
                                                                  HAS
                                                                  (France)

The European Patients Academy
on Therapeutic Innovation (EUPATI)
recommends that HTA organisations                                                                                                  PBAC
develop frameworks to systematically                                                                                               (Australia)
incorporate patient input to HTAs.5

These countries are incorporating patient preference through the use of
discrete choice experiment (DCE) methodology in their HTA decision-making3:

Germany’s IQWIG recommends                        England’s NICE has used it                    Sweden recommends use when
its use to estimate the aggregate                 in the unmet need section of                  the QALY is inappropriate, such
benefit in economic evaluations3,4                NICE dossiers and selection                   as when evaluating changes in
                                                  of trial endpoints3,6                         short-term pain3

HCP=healthcare provider; HAS=Haute Autorité de Santé; NICE=National Institute for Health and Care Excellence; SMC=Scottish
Medicines Consortium; IQWIG=Institute for Quality and Efficiency in Healthcare; PBAC=Pharmaceutical Benefits Advisory Committee;
QALY=quality-adjusted life-year.
What is DCE?7
Discrete choice experiment (DCE) quantifies preference values toward various treatment attributes, allowing
for estimation of the relative importance of different aspects of care or outcomes. Consideration of these
stated priorities during HTA would help ensure access to products which deliver best value by addressing
stated priorities.
Case Study: DCE in nmCRPC
For non-metastatic castration-resistant prostate cancer (nmCRPC), DCE can be used to capture treatment
preferences and offer insights into patient and stakeholder needs.
Qualitative phase identifying treatment needs and important attributes1
Fatigue, skin rash, cognitive problems, serious falls, serious fractures, overall survival, time to pain progression
Quantitative phase capturing choice between hypothetical treatment options differing in
attribute performance1,2
(patients: N=143; caregivers: N=149; physicians: N=149)
14 treatment choice questions, each comparing 2 hypothetical medication profiles varying on the 7 attributes1,2

  Number of months of overall survival that patients, caregivers, and physicians
     were willing to trade in return for an improvement in adverse events1,2
                                                             Patient                              Caregiver                            Physician
                                                              (N=143)                               (N=149)                              (N=149)
              Cognitive problems
              (moderate to none)                         >9 months                              >9 months                            2.5 months

              Fatigue
              (moderate to none)                         >9 months                              8.4 months                           0.8 months

              Serious fractures
              (5% to none)                               >9 months                              >9 months                            5.3 months

                                                                  Key Takeaways
• Since patients with nmCRPC are generally asymptomatic, AEs from treatment are of even greater
  importance when patients are considering treatment options
• These study results indicate that nmCRPC patients and caregivers preferred treatments with lower AE
  burden and were willing to forego substantial duration of OS to reduce the risk and severity of AEs1
• Among the AEs evaluated, patients most valued the reduction of serious fracture, serious fall, and
  cognitive problems1
• Patient preferences can differ from those of physicians, allowing the patient to provide real-world
  understanding of their treatment, which can help improve shared decision-making

                                              See more on the Bayer Exhibitor page
AE=adverse event; OS=overall survival.
References: 1. Srinivas S, Mohamed AF, Appukkuttan S, et al. Patient and caregiver benefit-risk preferences for nonmetastatic castration-resistant prostate cancer
treatment. Cancer Med. 2020;9(18):6586-6596. 2. Srinivas S, Mohamed AF, Appukkuttan S, et al. Physician preferences for non-metastatic castration-resistant prostate
cancer treatment. BMC Urol. 2020;20(1):73. doi:10.1186/s12894-020-00631-4 3. Marsh K. Patient preferences in health technology assessment in Europe: recent advances
and future potential. The Evidence Forum. Fall 2019. https://www.evidera.com/patient-preferences-in-health-technology-assessment-in-europe-recent-advances-and-
future-potential/. Accessed May 17, 2021. 4. Chachoua L, Dabbous M, François C, Dussart C, Abelléa S, Toumi M. Use of patient preference information in benefit-risk
assessment, health technology assessment, and pricing and reimbursement decisions: a systematic literature review of attempts and initiatives. Front Med. 2020;7:543046.
doi: 10.3389/fmed.2020.543046 5. Hunter A, Facey K, Thomas V, et al. EUPATI Guidance for Patient Involvement in Medicines Research and Development: Health
Technology Assessment. Front Med. 2018;5:231. doi: 10.3389/fmed.2018.00231 6. National Institute for Health and Care Excellence. Baricitinib for moderate to severe
rheumatoid arthritis. http://www.nice.org.uk/guidance/ta466. Published August 9, 2017. Accessed May 17, 2021. 7. Trapero-Bertran M, Rodriguez-Martin B, Lopez-Bastida
J. What attributes should be included in a discrete choice experiment related to heath technologies? A systematic literature review. PLoS One. 2019;14(7):e0219905. doi:
10.1371/journal.pone.0219905

             © 2021 Bayer. All rights reserved. BAYER and the Bayer Cross are registered trademarks of Bayer. MAC-PF-ONC-ALL-0038-1 06/21
Online MSc Health Technology Assessment
Want to be a 21st century HTA practitioner?             Students may then select from a range of optional
Governments around the world are using Health           courses:
Technology Assessment (HTA) to inform
decision-making. Get involved and enhance                 •   Outcome measurement and valuation for HTA
your career by acquiring quantitative and qualitative     •   Qualitative research methods for HTA
research skills in support of HTA. Join our online        •   HTA in a global context
distance learning programme, 2.5-6 years part-time        •   Survival analysis for HTA
(MSc), 2-4 years part-time (PgDip), 1-2 years             •   Foundations of decision analytic modelling
part-time (PgCert). The online delivery includes          •   Data science
video presentations by teaching faculty, live             •   Maximising the value of clinical trial data
lectures over the internet, weekly exercises,
directed readings and student/faculty interaction on
discussion forums.                                      Students can study to Certificate, Diploma or Masters
Our MSc comprises the following core courses:           (includes a research project) level.

                                                        For more details please visit
  •   HTA: policy and principles                        www.gla.ac.uk/hta
  •   Statistical methods for HTA and
		    evidence-based medicine
  •   Health economics for HTA                          Continuous Professional Development (CPD)
  •   Research project                                  Our CPD programme includes our new live, online
		    (core ‘course’ only for MSc level)                course Maximising the Value of Clinical Trial Data. In
                                                        addition, the online MSc HTA courses listed above
                                                        can be taken as non-accredited CPD. They run at the
                                                        same time as the MSc courses so please visit
                                                        www.gla.ac.uk/hta for more details of dates.
Research
Our research is divided into eight programmatic          Analysis of Linked Health Data
themes:                                                  This programme encompasses all research
                                                         work in HEHTA that is associated with statistical,
Global HTA
                                                         epidemiological and economic analysis of linked
This programme considers HTA and decision-making
                                                         health data sets.
in different contexts, exploring variation, within and
between, high-income and low- and middle-income          Incorporating Perspectives and Experiences
countries.                                               This programme focuses on the application of
                                                         qualitative methods of data collection and analysis,
Economics of Population Health
                                                         and evaluation of interventions to improve health.
This programme is concerned with the development
of methods and related empirical work associated         Evidence Synthesis
with the economic evaluation of ‘up-stream’              This programme encompasses all research work
population health interventions.                         associated with systematic review, and meta-analysis
                                                         of direct, indirect and network evidence.
Decision Analytic Modelling
The programme encompasses research work
associated with conducting an evaluation using
modelling or simulation methods. It cuts across
and interacts with many of the other programmatic
themes of HEHTA.
                                                         Postgraduate Research opportunities are available,
Economic Evaluation alongside Clinical Trials
                                                         with many of our staff supervising doctoral and
This programme encompasses all research work
                                                         postgraduate research students in various subject
associated with conducting an economic appraisal
                                                         areas relating to health economics and HTA. Our
as part of a clinical trial.
                                                         students’ work results in high quality publications,
Economics of Precision Medicine                          international conference presentations and
This programme focuses on evaluation of stratified       contributes to HEHTA’s international reputation
medicine and early stage technologies.                   across our eight research themes.

Contact us:
Health Economics and Health Technology Assessment (HEHTA)
1 Lilybank Gardens, Glasgow G12 8RZ
0141 330 4010
www.gla.ac.uk/hehta
Twitter: @HEHTAGlasgow                                                                                       © University of Glasgow 2021
                                                                           Design: MVLS Design and Communication, University of Glasgow
                                                                                      The University of Glasgow, charity number SC004401
Innovating for minimally invasive care
Intuitive (Nasdaq: ISRG), headquartered in Sunnyvale,                  Intuitive brings more than two decades of leadership
California, is a global technology leader in minimally                 in robotic-assisted surgical technology and solutions
invasive care and a pioneer of robotic-assisted surgery.               to its offerings and develops, manufactures, and
As part of our mission, we believe that minimally                      markets the da Vinci surgical system and the Ion
invasive care is life-enhancing care. Through ingenuity                endoluminal system.
and intelligent technology, we expand the potential
of physicians to heal without constraints.                             Learn more at Intuitive.com.

8.5 million+
Number of minimally invasive procedures
                                                                       24 thousand+
                                                                       Total number of peer reviewed
performed worldwide through 2020 using                                 scientific articles that reference
the da Vinci surgical system.                                          da Vinci surgical systems*.

1.2 million+
Number of procedures performed in
                                                                       25.4 seconds
                                                                       How often a surgeon begins a procedure
2020 using the da Vinci surgical system.                               using the da Vinci surgical system.

67
countries

5,989
da Vinci systems
around the world

As of December 15, 2020.
*

© 2021 Intuitive Surgical, Inc. All rights reserved. Product and brand names/logos are trademarks or
registered trademarks of Intuitive Surgical or their respective owner. See www.intuitive.com/trademarks
cambridge.org/thc
Official Journal of

                                   27/01/20 12:35 PM
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      Technology
      Assessment
      in Health Care
      serves as a forum for the wide range of
      health policy makers and professionals
      interested in the economic, social, ethical,
      medical and public health implications of
      health technology.

      Looking for articles on
      Innovation Through HTA?
      We have over 1,200 articles on innovation.
      Browse our articles at cambridge.org/THC.

Official Journal of
Executive MSc
                                    Evaluation of Health
                                    Care Interventions
                                    and Outcomes
                                    In collaboration with the National Institute
                                    for Health and Care Excellence (NICE)

                                      Study alongside full-time work

         The combination            The Executive MSc in Evaluation of Health Care Interventions
                                    and Outcomes delivers training in health services research,
         of LSE’s world-            health economics, health outcomes research and health policy.
                                                                                                        75% LSE
                                                                                                        25% NICE

leading teaching and                The two-year programme has been developed in collaboration
research excellence and             with NICE, known internationally for the scientific rigour of       Teaching
                                    its approach to evaluating the effectiveness and value of
NICE’s standing as a
                                    medicines, medical technologies, treatments and interventions.
national authority and
global leader in health             For working health professionals
                                    The programme is designed for professionals from a wide
technology assessment
                                    range of backgrounds in the health sector who are looking
and guidance offers an              to progress in their career and develop as health policy
                                                                                                         2 years

unparalleled degree of              leaders by building on their skills in health economics, health
                                    outcomes research, and management.
rigour and professional
relevance.                          Teaching timetable
                                    Over two years, the courses will be delivered in four              8 courses
       Professor Elias Mossialos    intensive two-week teaching blocks at the London School
  Deputy Head of Department and     of Economics and Political Science. This schedule allows
           Director of LSE Health   participants to complete the degree alongside full-time work.

                                      Visit our website to apply                                       4 teaching
                                                                                                      blocks at LSE
Courses
 Year 1

Introduction to Evaluation in Health Care
Gain an in-depth overview of the key principles and models used to evaluate health
care interventions, programmes and policies.

Systematic Review and Meta-analysis
Learn the key principles of evidence review and synthesis needed to interpret
existing evidence to evaluate health care interventions.

Economic Evaluation in Health Care
Develop your strategic decision-making skills by learning how to understand,
critically appraise, develop, and interpret cost-effectiveness analyses to make
specific recommendations and define best practice.

Dissertation in Evaluation of Health Care Interventions and Outcomes
Explore a topic of your choice in the field of health services research and health
policy, and integrate the methodology and knowledge learned across your courses
to address a key issue.

 Year 2

Quasi-experimental Evaluation of Health Care Programmes
and Policies
Gain the skills needed to design, critically appraise, and conduct quasi-
experimental studies evaluating health policies, programmes, and interventions.

Randomised Evaluation of Health Programmes and Policies                                               NICE has 20
Learn to design and conduct a randomised evaluation through hands-on and                              years’ experience
intuitive training while exploring the rationale of best-practice experimental design.
                                                                                           in evidence-based health
Statistical Methods in Health Care Economic Evaluation                                     care decision making
Develop the statistical and modelling techniques necessary to apply economic
evaluation to the health care sector by mastering a range of statistical methods.
                                                                                           and we are delighted to
                                                                                           be able to partner with
Principles of Health Technology Assessment
                                                                                           LSE in order to share
This course is aimed at introducing the key principles of health technology
assessment, its operational modalities, the different models of value assessment           this expertise amongst
and how they link to decision-making.                                                      professionals who are
                                                                                           looking to enhance their
Please note that course regulations may change. For the most up-to-date list of courses,   skills in this area.
please visit: lse.ac.uk/NICE-exec-MSc

                                                                                                               Jeanette Kusel
  Apply now to secure your place                                                            Director for NICE Scientific Advice
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