Impact of COVID-19 on Patients with Obsessive Compulsive Disorder: A Review

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International Journal of Science and Healthcare Research
                                                                                        Vol.5; Issue: 3; July-Sept. 2020
                                                                                                     Website: ijshr.com
Review Article                                                                                         ISSN: 2455-7587

      Impact of COVID-19 on Patients with Obsessive
             Compulsive Disorder: A Review
                 Sakshi Bhardwaj1, Abhinav Bhardwaj2, Ravi Parkash3
 1
  Senior Resident, Dept. of Psychiatry, Maharishi Markandeshwar Institute of Medical Sciences and Research
  2
  Senior Resident, Dept. of Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research
                    3
                      Senior Resident, Dept. of Psychiatry, Pt. B.D. Sharma PGIMS Rohtak
                                        Corresponding Author: Ravi Parkash

ABSTRACT                                                    case on 30th January 2020. [1] Countries
                                                            have taken extreme steps to reduce the
The unpredictability and uncertainty of the                 transmission of corona virus such as total or
COVID-19 pandemic, lockdowns, social                        partial lock down with social distancing,
distancing, quarantine, isolation and the                   quarantine, and isolation. [2] The pandemic
forthcoming economic breakdown can increase
                                                            has increased the burden of psychiatric
the risk of mental health problems. This review
assesses the effect of corona pandemic on OCD               illnesses among the population either due to
patients. Various studies suggest that OCD                  emergence of de novo symptoms or due to
affect up to 3.1% of the population and is                  loss to follow up of patients and inability to
associated with substantial disability and                  take medications. Among the individuals
decreased quality of life. One of the main                  with mental illnesses of various types, OCD
symptoms of OCD involves fear of                            is the one which is directly affected by the
contamination and washing compulsions.                      worsening outbreak of COVID-19. The
Recent pandemic declared by WHO has put                     peak in anxiety about the virus has
certain recommendations to tackle this viral                exacerbated the existing obsessive fears of
illness such as hand hygiene, sanitization,                 contamination and harmful compulsive
avoiding contact with people and surfaces which
                                                            actions in some people with OCD. [3] Print,
overlaps with OCD symptoms. People with pre-
existing OCD are prone to relapses, the fear of             electronic and social media are flooded with
transmitting COVID-19, distress and suicidal                advisories issued by governments and other
ideas. Despite the nature of their conditions,              national & international agencies. The
these people must adhere to routine processes,              celebrities, public figures, governments
such as washing hands, wearing masks and                    bodies dealing with health-related affairs are
gloves, and sanitizing hands. So, it is important           advising people to wash hands repeatedly,
for mental health professionals to identify the             patients of OCD may find it difficult to
high risk individuals who are at risk of getting            resist. [4] The role of media in exacerbating
OCD or to identify triggering factors in already            the symptoms of OCD is supported by few
diagnosed OCD.                                              studies. [5] Prestia et al. carried out a study
                                                            to evaluate the changes in OCD symptoms
Keywords: Obsessive compulsive disorder,
pandemic, COVID 19                                          before and after quarantine in a group of
                                                            patients who were on psychiatry treatment
INTRODUCTION                                                of OCD (DSM 5 criteria) during the last 6
       The first case of corona virus disease               months. A significant increase was seen in
2019 (COVID-19) emerged in Wuhan,                           severity of obsession and compulsion
China in December 2019. It spread                           symptoms on Yales Brown Obsessive
throughout the world within less than three                 Compulsive Scale (YBOCS). [6] In an
months. India recorded its first COVID-19                   another study by Ismail et al. in 598 Turkish

                 International Journal of Science and Healthcare Research (www.ijshr.com)                          581
                                     Vol.5; Issue: 3; July-September 2020
Sakshi Bhardwaj et. al. Impact of COVID-19 on patients with obsessive compulsive disorder: a review

adolescents, the relationship between fear of           prevalence rate of sub threshold OCD up to
COVID-19 and OCD was analyzed and                       12.6%. Community studies of OCD have
found the role of emotional reactivity,                 reported a slight female predominance.
experiential avoidance and depression-                  OCD is highly comorbid with other
anxiety in this relationship. Experiential              psychiatric illnesses, most commonly
avoidance strategies such as distraction,               depression and anxiety disorders, high risk
inhibition, denial or suppression were used             for suicidal behavior and high rates of
to control negative experiences. [7] Hisato et          substance and alcohol use disorders. [10]
al. investigated the acute impact of the
COVID-19 pandemic on the changes of                     Effect of COVID 19 pandemic on OCD
severity or symptomatology of OCD                       patients
symptoms in 60 full or partial remitted OCD                     Obsessive-compulsive          disorder
patients who were treated for more than 3               (OCD) is characterized by obsessions
years in OCD clinic who directly visited the            (recurrent and persistent thoughts that are
clinic from April 7 to May 2, 2020 in                   experienced as intrusive and inappropriate,
emergency in Japan. Their OCD symptoms                  causing marked anxiety) and repetitive
were reassessed at the time when they came              compulsions (repetitive behaviors or mental
to clinic in the emergency. The results                 acts carried out in response to an obsession
showed that those subjects with OCD                     and are aimed at preventing or reducing
symptoms badly affected by COVID-19                     anxiety). These symptoms of OCD often
were significantly more likely to have                  interfere with a person’s normal routine,
higher trait anxiety, depressive status,                occupation, or social activities and
higher prevalence of generalized anxiety                relationships. Individuals those who are
disorder     and       contamination/washing            already suffering with OCD specifically
symptoms specifically associated with virus             contamination or hypochondriacal type of
respiratory infection such as Influenza                 worries or having perfectionistic type of
infections at the assessment before the                 personality might be more vulnerable to this
spread of COVID-19. [8]                                 pandemic
                                                                World Health Organization (WHO)
METHOD OF CONDUCTING REVIEW                             and Centers for Disease Control and
        Articles that assessed the impact of            Prevention (CDC) recommended the social
COVID 19 pandemic on OCD patients were                  distancing and hand hygiene as the major
identified through searches of the PubMed,              strategies recommended for control of
EMBASE, and Google Scholar databases                    spread of COVID 19 infection. This has led
for articles published in English between               to an increase in the demand for sanitizers,
January 2020 and August 2020. The search                soaps and gloves. Every media source is
combined        the     terms     obsessions,           stressing on the importance of hygienic
compulsions, challenges faced due to                    measures, washing hands and prevention of
COVID 19 pandemic etc. Additional articles              contamination. It has led to the increased
were identified by a manual search of the               stress in the patients of preexisting OCD
reference lists of the identified articles and          due to doubts with hygiene and the
recent review articles.                                 compulsive need to stay clean. OCD
                                                        individuals with fear of contamination may
Prevalence of OCD in general population                 spend hours worrying about the possibility
        According to the World Health                   of contacting an infections illness, avoiding
Organization, OCD is the sixth most                     potential contaminants such as not touching
disabling psychiatric disorder. The lifetime            certain surfaces or decreasing social
prevalence of OCD is 2.3% according to                  contacts, or engaging in compulsive
National Comorbidity Survey Replication                 washing behaviors of different sorts such as
reports. [9] A few studies reported                     taking excessively long showers or spending

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                                    Vol.5; Issue: 3; July-September 2020
Sakshi Bhardwaj et. al. Impact of COVID-19 on patients with obsessive compulsive disorder: a review

hours washing or disinfecting hands. [8]                   The prompting of family to ensure strict
Need for certainty can lead to excessive,                   hygienic measures and vice versa.
intense, and repeated reassurance seeking.               The constant loading of information
Inconsistencies between the sources of                      from various media sources about
information can lead to further information-                possibility of the virus to stay active on
seeking from a range of resources, some of                  various inanimate surfaces, hence
which are likely to be more accurate than                   adding to the thoughts of contamination.
others. [11] High levels of fear of COVID-               Increased ruminations and repeated
19 may cause irrational and unclear                         washing (or even bathing), can be
thoughts. Apart from the panic, health                      ‘normalized’ at the face of a pandemic
anxiety, mass hysteria and loneliness of                    response       as     an      exaggerated
isolation created due to COVID pandemic,                    precautionary measure.
the prominence of obsessive-compulsive                   Stocking of masks, soaps, sanitizers,
symptoms has largely been neglected.                        disinfectants that can lead to hoarding
Worldwide there have been reports of                        and panic shopping.
increased symptoms, distress and concern                        Hoarding disorder is considered as a
about this illness. [12] The pandemic can act           part of Obsessive Compulsive (OC)
as a triggering factor for underlying OC                Spectrum in DSM 5. Apart from hoarding
spectrum disorders in a genetically prone               items of little use, need-based hoarding can
person, shift the balance from ‘normal’                 increase both in OCD and hoarding
obsessions to a pathological OC pattern, or             disorder. This also includes medications
can worsen an already existing OC disorder.             used for symptomatic treatment of flu like
                                                        analgesics, anti-inflammatory and anti-viral
The presentations of symptoms in OCD                    drugs. This can lead to shortage of supplies,
in the pandemic                                         agitation in the public and patients with
        The various presentations of                    genuine needs being deprived of them.
symptoms can be as follow-                              Subsequent anxiety might lead to obsessive
1. New onset of symptoms of OCD related                 use of medications like hydroxychloroquine
    to fears of COVID-19                                (HCQ), which is recently mentioned in the
2. Current worsening in the severity of                 guidelines for COVID-19. It can be cardio-
    OCD in patients who have been on                    toxic and even life-threatening for certain
    follow-up for OCD                                   individuals who are taking medications
3. Relapse in those who previously                      without adequate supervision.
    responded/remitted with treatment                           Due to these reasons mentioned
4. Factors affecting the worsening of OCD               above, early identification and proper
    following the COVID-19 pandemic                     treatment by a qualified psychiatrist and
                                                        team is the key in management.
Reasons why OCD patients are at most
risk                                                    Pharmacological management of OCD
        The reasons why OCD patients are                during COVID Pandemic
more prone due to COVID pandemic are as
                                                         Confirm Diagnosis - Identify whether
follow-
                                                           the current symptoms are an aggravated
 The increased demand for hand washing                    response to recent stressful events or the
 The importance for ‘proper’ hand-                        worsening of obsessive-compulsive
    washing steps as per recommendations                   symptoms.
    can add to a ritualistic pattern.                    Comorbid conditions - Identify the
 The need to keep the hands clean every                   presence of comorbid conditions such as
    time a person comes from outside or                    anxiety disorder, depression, bipolar
    there is a suspected exposure can add to               disorder, or posttraumatic stress disorder
    the distress cognitively.                              (PTSD), or any other medical condition

                International Journal of Science and Healthcare Research (www.ijshr.com)                  583
                                    Vol.5; Issue: 3; July-September 2020
Sakshi Bhardwaj et. al. Impact of COVID-19 on patients with obsessive compulsive disorder: a review

    which may influence or interfere in the                 health crisis can persist for some time,
    treatment of OCD.                                       and they need to manage their stress
   Pharmacological treatment                               levels over time (e.g., long-term routines
    - SSRI (Drug of Choice)                                 of     mindfulness      techniques,    and
    - Another SSRI if no response to first                  exercise).
        SSRI                                               Cognitive behavioral therapy (CBT) is
    - Clomipramine as third choice                          considered as a first-line intervention for
   Adequate dosing - Gradually increase                    OCD. In ERP, people are being exposed
    the suboptimal dose, pay attention to                   to things that trigger their OCD, so those
    contraindications and adverse effects.                  with contamination fears may be asked
   Adjuncts - Low-dose antipsychotics can                  to touch things in public places, then
    be used as an adjuncts (eg, risperidone,                resist washing their hands which would
    olanzapine, aripiprazole, quetiapine,) if               counter public health recommendations
    the response is inadequate or if tics are               in COVID pandemic and can be
    present.                                                dangerous to the patient. In vivo
   Adherence - Ensure patient is taking                    exposure should be paused and ERP
    medications in adequate dose and                        interventions should be modified
    regularly. Involve family/caregivers if                 according to individual case. For
    adherence is in question.                               patients whose exposure is unrelated to
   Assess suicidal risk- Some patients,                    contamination, ERP treatment plans can
    including those with severe obsessions,                 be continued. Balancing the risk of a
    comorbid depression, bipolar disorder,                  patient contracting COVID-19 during
    impulse control disorders, substance use                ERP with the potential benefit of ERP
    disorders, personality disorders and                    on     reducing      obsessive-compulsive
    eating disorders may be at increased                    symptoms should be central to treatment
    risk. Additional COVID-related factors                  planning, considering both the latest
    may potentially increase the suicide risk               information and guidelines about the
    such as recent increase in OCD severity,                pandemic with the degree of impairment
    family member found positive for                        and distress caused by OCD. [13]
    COVID-19 or finding the effects of                     Activity scheduling and structuring the
    quarantine or isolation distressing.                    day to include physical activity,
   Telemedicine - include telephone,                       enjoyable activities, practices that
    WhatsApp, text messages, email or                       enhance sleep, and mindfulness. Patients
    video calls. Use teleconsultation                       under quarantine or staying at home
    services as per telepsychiatry guidelines.              under restrictions are at great risk of
                                                            circadian rhythm disruption which can
Non - pharmacological management of                         increase anxiety and worsen OCD
OCD during COVID Pandemic                                   symptoms while regular circadian
 Psychoeducation - Give information                        rhythms and regular physical activity
   about the risks and impact of COVID-19                   will help in reducing anxiety.
   on physical and mental health. This                     Support to caregiver: family members
   includes the difficulties in managing the                and caregivers of patients with OCD are
   uncertainty associated with the virus but                at increased risk of developing stress
   it might be challenging for some people                  related disorders due to the worsening of
   with OCD, hypochondriasis or anxiety.                    patients’ symptoms and may need
   Highlight the need for physical                          additional      support.     Parents    are
   distancing (staying at home except for                   encouraged to engage in joyful activities
   essential tasks like grocery shopping),                  with their child.
   with special precautions for the elderly.
   Patients need to understand that this

                International Journal of Science and Healthcare Research (www.ijshr.com)                  584
                                    Vol.5; Issue: 3; July-September 2020
Sakshi Bhardwaj et. al. Impact of COVID-19 on patients with obsessive compulsive disorder: a review

Other measures to deal with OCD during                      obsessions and compulsions can lead to
pandemic                                                    dermatological      conditions,    chronic
 Balanced information-Tell the patients                    stress, insomnia and high risk for
   about the known risks and impact of                      suicide.
   COVID-19 on their symptoms and clear                    Training of Primary health-care
   their myths and doubts if any. For                       workers at various sites need to be done
   example, patients who have washed                        to identify OC complaints and the
   their hands for hours and bleached or                    necessary referrals.
   even boiled their hands.                                Limit media use- Patients are asked to
 Clear myths-Some patients with OCD                        check news once a day for a maximum
   thinks whether it is safe to touch a                     of five minutes, or watch the evening
   newspaper or if they can catch the virus                 news once a week, or decide not to
   if they go outside, even if no one is                    check news at all.
   around. Some wonder if they should                      Practice self-compassion - Tell the
   'quarantine' a package or wear gloves to                 patient that it is normal to be anxious
   bed. It will be helpful to show them the                 about the coronavirus. COVID-19
   public health guidance of the WHO or                     worries many people, including those
   CDC advising that 20 seconds of hand                     who don't have OCD. Encourage
   washing is adequate.                                     patients to be vigilant if they experience
 Check source of information-Some of                       an increase in OCD symptoms. Remind
   the sources of information about                         them that it’s not their fault and to do
   COVID-19 are not factually correct and                   what they can to keep their compulsions
   that people get incorrect information                    in check without trying to be perfect.
   from watching these news all day and                    Follow advice from heath care
   being bombarded with information                         professionals and follow guidelines for
   which makes their symptoms a thousand                    social distancing.
   time worse. Therefore, patients should                  Take time to do things you enjoy such
   be advised to limit news to half an hour                 as contact with family and friends, listen
   twice daily.                                             to music, read good books, get some
 Empathetic attitude towards patients-                     fresh air, sing or dance, watch TV and
   Clinicians should listen to patients’                    movies that make you happy, and take
   symptoms           and         complaints                every opportunity to relax.
   empathetically and should follow a
   compassionate, calming and culturally                CONCLUSION
   sensitive approach to inform all                             Providing accurate and personalised
   interventions. Empathy from close                    information on relevant risks can prevent
   friends and family is helpful.                       the development or exacerbation of mental
 Psychoeducation of the patients and                   health problems. It is important that
   families, debunking misinformation                   clinicians and policymakers should be
   about the pandemic, using the                        aware of the potential increased risk of
   psychiatric social work support to                   relapse among those with an underlying
   follow-up on severe and treatment                    OCD diagnosis during infectious disease
   resistant patients, ensuring drug                    pandemics and proactive efforts are needed
   compliance are necessary steps to help               to support this vulnerable population. As
   people who are in need. It is vital to               mental health professionals (MHPs), we
   explain to them the context and                      need to assess and educate all patients of
   circumstances of washing and make                    anxiety disorders and OCD visiting us in
   them realize what is ‘out of proportion’.            outpatient services. Providing alternative
   Similarly, any unnecessary hoarding                  channels of care like telephonic helplines
   needs to be minimized. Uncontrolled                  and online consultations might also help.

                International Journal of Science and Healthcare Research (www.ijshr.com)                  585
                                    Vol.5; Issue: 3; July-September 2020
Sakshi Bhardwaj et. al. Impact of COVID-19 on patients with obsessive compulsive disorder: a review

Educating people about the adverse                      7. Secer I, Ulas S. An Investigation of the
psychological effects of such pandemic                      Effect of COVID-19 on OCD in Youth in
scenarios, promoting behavioural health                     the Context of Emotional Reactivity,
promotion, integrating with primary health                  Experiential Avoidance, Depression and
care, solving issues and helping COVID-19                   Anxiety. Int J Ment Heal Addict. 2020; 1-
                                                            14.
patients can play a key role in preventing              8. Matsunaga H, Mukai K, Yamanishi K.
mental health crisis.                                       Acute impact of COVID-19 pandemic on
                                                            phenomenological features in fully or
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