Corona Virus: Overview and Dealing with it - Dr. Amine Marref March 17, 2020
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Corona Virus: Overview and Dealing with it Dr. Amine Marref amine@marref.org March 17, 2020
Roadmap 1 Naming 6 Symptoms 2 Origin of Virus 7 Contracting the 3 Health Risk Disease 4 Transmission 8 Fatalities 9 Concluding 5 Prevention Remarks
Naming Scientific name for disease: CoronaVirus Disease (CoViD-19)1 Scientific name for virus responsible for disease: Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2)2 The word Corona is the Latin of the English word Crown. The corona disease is caused by a crown virus which is called so because apparently the first person to discover this group of viruses thought they look like little crowns. 1 World Health Organization (WHO): www.who.int 2 World Health Organization (WHO): www.who.int
Naming An electron-microscope picture of SARS-CoV-23 3 Rocky Mountain Laboratories (RML): www.niaid.nih.gov
Origin of Virus There are quite a few hypotheses that explain the origin of the disease. The virus was created in labs to be used as a biological weapon. The virus was created in US labs and was launched in China. The virus was created in Chinese labs and was launched by mistake in China. There are at least two books published in the past and that discuss strikingly similar events. End of Days by Sylvia Browne, 2008 which identifies 2020 as the year where a virus outbreak occurs that causes a severe pneumonia-like disease worldwide. The Eyes of Darkness by Dean Koontz, 1981 which discusses a virus called Wuhan-400 (at least in later prints) that also takes the world by surprise and no prizes for noticing it: it originates in Wuhan, China!
Origin of Virus The virus is caused by bats when bitten by them, eating them, or eating something bitten by them. Bats are the source of previous viruses such as EboV, SARS-CoV, and MERS-CoV4 . It has been reported that people in Wuhan – the place where the virus was first discovered – consume exotic animals such as bats. 4 www.who.int
Health Risk According to Johns Hopkins University5 , the number of fatalities caused by the Covid-19 according to the latest update while writing these lines (2020-03-17-14:00) is 3.96% which corresponds to 7,330 deaths out of 185,067 case worldwide. According to the same source6 , the number of fatalities from seasonal flu is from 291,000 to 646,000 out of a billion case worldwide annually which corresponds to a fatality rate of 0.06%. 5 Johns Hopkins University: coronavirus.jhu.edu/map.html 6 Johns Hopkins University: coronavirus.jhu.edu/map.html
Health Risk According to the World Health Organization7 , since MERS-CoV was discovered it infected 2494 persons of which it killed 858 i.e. with fatality rate of 34.4%. According to National Health Service8 , since SARS-CoV was discovered, it infected 8098 persons of which 774 died i.e. with fatality rate of 9.5%. 7 World Health Organization: who.int 8 National Health Service: nhs.uk
Health Risk The following table summarizes the previous statistics. Notice that there is an inversly-proportional relationship between the spreading force of the virus quantified by the number of cases worldwide, and the deadliness of the virus quantified by the number of fatalities it causes. So far, it seems that the virus has a large spreading force with relatively small deadliness. Virus Name Outbreak Cases Fatalities Ratio SARS-CoV 2003 8,098 774 9.5% MERS-CoV 2012 2,494 858 34.4% SARS-CoV-2 2019 185,067 7,330 3.96% InfluenzaVirus - 1,000,000,000 291,000-646,000 0.06%
Health Risk The virus is reported to infect pretty much anybody, but it is most deadly for certain classes of people. Old people. People with chronic diseases such as cardiovascular disease, diabetes, chronic respiratory disease, hypertension, and cancer. 9 9 Centers for Disease Control and Prevention (CDC): cdc.gov
Health Risk When the virus penetrates the host’s body cells, it starts making copies of itself and spread until it sometimes reaches the alveoli in the lungs and causes an inflammation that makes it hard for them to do their job of exchanging oxygen and carbon dioxide which eventually causes breathing difficulties. 10 11 The virus can spread to the digestive system and other organs such as the heart, liver, and kidneys which could result in a very strong immune-system response that causes inflammations which make things a lot worse. 10 Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer, February 2020 11 Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection, February 2020
Transmission The corona virus is contagious, and transmission between humans occurs primarily through coughing and sneezing. It is possible for the droplets that come out from the mouth or nose while coughing or sneezing to travel as far as 10 meters. The droplets contain the virus in different quantities: a person that is showing symptoms will produce droplets that contain more quantities of the virus compared to a person who is asymptomatic.
Transmission The virus is transmitted secondarily via skin contact e.g. handshaking or touching a surface to which the virus has attached itself. The virus attaches itself to surfaces using hydrogen and hydrophilic bonds. A recent study12 shows that SARS-CoV-2 can stick for days to plastic and stainless steel surfaces, and for hours to copper and cardboard surfaces. 12 Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1, March 2020
Transmission A recent study13 discovered the virus in the human feces of infected people, but did not conclude whether or not the virus is viable – in that state – to infect people. There are ongoing studies 14 on whether or not recovered cases can become re-infected and spread the virus 13 Study: COVID-19 may spread in several different ways: cidrap.umn.edu 14 Positive RT-PCR Test Results in Patients Recovered From COVID-19, February 2020
Prevention World health organizations and institutions recommend the following precautionary methods to avoid contracting the disease. Staying at home if possible, and limiting outside activity as much as possible except for the absolute necessities. Washing hands thoroughly with soap by rubbing it forcefully on the palms, the back of the hands, between fingers, and in the crevices of the nails. This should become a second nature: do it when you are home, before eating, after using the bathroom, after sneezing, when handling cash, etc. Avoid touching the face, nose, mouth, and eyes (probably the hardest!). Walking away from any person that coughs or sneezes.
Prevention Adopt a minimalist-greeting style: greeting people verbally (use telepathy if you can), and avoid handshakes, kissing, hugging, etc. Make sure to cover the toilet seat before flushing to avoid the volatile droplets (at least until it is confirmed whether or not the virus is transmitted this way). Avoid using public loos.
Humane Prevention It is easy for people to lose their humanity in case of pandemics and disasters. Walking away from a person who sneezes or coughs should be done tactfully e.g. pretending that you want to make a phone call. Do not walk away from people while looking at them with fright or contempt. They might have contracted the virus, you might too! Avoiding handshake should be done with a warm smile.
Humane Prevention Panic-buying will cause food to become scarce and therefore prices will go up. If the pandemic in your area does not recede within a couple of weeks or a month, you will run out of the food you hastily stockpiled. However this time, you might not find food to buy because the prices just went crazy. There are people who only earn enough to buy food for one day, do not add to their miseries.
Symptoms The corona disease shares many symptoms with seasonal flu: fever, dry cough, fatigue, and sputum production. The corona disease differs from the flu in that it causes shortness of breath in one out of five cases who have contracted the disease 15 (see next figure). 15 World Health Organization (WHO): who.int
Symptoms Covid-19 Symptoms with Probability of Occurrence based on Previous Cases Fever 87.90% Dry Cough 67.70% Fatigue 38.10% Sputum Production 33.40% Shortness of Breath 18.60% Musle Pain or Joint Pain 14.80% Sore Throat 13.90% Headache 13.60% Chills 11.40% Nausea or Vomiting 5% Nasal Congestion 4.80% Diarrhea 3.70%
Symptoms The following table 16 compares the symptoms of Covid-19, seasonal flu, and common cold. As can be seen, it is difficult without proper medical testing to identify Covid-19 because of the similarity in symptoms between the three diseases. Fortunately, Covid-19 is distinguishable because it causes shortness of breath (blue cell). Unfortunately, shortness of breath shows that the disease can become dangerous for the infected person. 16 Deutsche Welle (DW): dw.com
Symptoms Symptoms Covid-19 Influenza Common Cold Dry Cough +++ +++ + Fever +++ +++ - Nasal Congestion - ++ +++ Sore Throat ++ ++ +++ Shortness of Breath ++ -- -- Headache ++ +++ - Pain ++ +++ +++ Sneezing -- -- +++ Fatigue ++ +++ ++ Diarrhea - ++ -- +++: Frequently, ++: Sometimes, +: Occasionally, -: Rarely, - -: Not Observable.
Contracting the Disease If you ever contract the disease, it is best to not panic, and think logically and scientifically. I have devised a flowchart (see next figure) that explains the optimal response a person that contract the disease might adopt. The devised response is not theoretically optimal, as this would imply rushing to a health center after you cough just once! However, the theoretically-optimal response will put a huge burden on health centers and their staff, which could lead to even more disastrous consequences. Instead of focusing on genuine cases and cases with high risks, health centers will be wasting their limited resources on cases that are otherwise perfectly fine.
Contracting the Disease You are showing some of the disease symptoms such as fever, dry cough, and fatigue. Perhaps you have the virus. You belong to You Belong to Group A Group B You are not in You are in There is a chance contact with a contact with a you have the virus. person from person from Contact the nearest Group B Group B health center. Wait until you feel Group A: People who are not better, and when you old and who have no chronic are with a person diseases from Group B, wear a Wait until you feel mask and do Group B: People who are old better everything possible to or who have chronic diseases not transmit the virus to them in case you have contracted the disease You are still sick and started You feel fine having difficulties breathing There is a good chance Maintain prevention you have the virus. measures Contact the nearest health center
Contracting the Disease The previous response flowchart is based on the following. If you are not old and you are not suffering from chronic diseases, in case you contract Covid-19 you will recover with a 98% chance. The disease is most dangerous when the virus reaches alveoli in the lungs, and this is easily detectable by starting to have shortness of breath. Old people and those with chronic diseases should take no chance. It is possible to add more elements to the diagram, such as data about contact with people who might already be sick (e.g. they are coming from an infected area). These new elements can be integrated to give a more informed response when showing disease symptoms.
Fatalities 17 The following table is taken from ”Our World in Data” Fatalities by Covid-19 by Age Group 0% 2% 4% 6% 8% 10% 12% 14% 16% 0-9 years 0% 10-19 years 0.20% 20-29 years 0.20% 30-39 years 0.20% 40-49 years 0.40% 50-59 years 1.30% 60-69 years 3.60% 70-79 years 8% above 80 years 14.60% 17 Our World in Data: ourworldindata.org
Fatalities 18 The following table is taken from ”Our World in Data” Fatalities by Covid-19 by Medical Condition Cardiovascular Dieases 11% Diabetes 7.30% Chronic Respiratory Disease 6.30% Hypertension 6.00% Cancer 5.60% No Health Condition 0.90% 18 Our World in Data: ourworldindata.org
Concluding Remarks At the time of writing these lines, the number of people who recovered from Covid-19 is 80,236 out of 185,067 cases i.e. with a recovery rate of 43.3%. Whereas the number of deaths does not exceed 4% most of which target a statistically-known group of people. According to this, there is an unwarranted panic from people which could itself far exceed Covid-19 in its devastation. My advice to you is to focus on preventing yourself from contracting the disease without fearing it unless you are from a vulnerable group, or if the virus becomes more powerful in future. Mass panic and hysteria is what is sought by satanic organizations to dominate people and their wealth.
Concluding Remarks I am not a health professional, I actually have a Ph.D. in Computer Science in Real-Time Systems. This however does not stop me from reading about the development of this pandemic, especially statistical research. I have put enough references for the reader for further research, and in cases where I show my own opinion, I clearly say so.
Concluding Remarks Do not fight the disease as an independent individual, fight it as a member of the society.
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