A COMPOSITE TRAPEZOIDAL AND SIMPSON RULE BASED TYPE2 FUZZY SYSTEM FOR ENHANCING AFDOA-HETRO-FRBCS - sersc
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International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 A COMPOSITE TRAPEZOIDAL AND SIMPSON RULE BASED TYPE2 FUZZY SYSTEM FOR ENHANCING AFDOA-HETRO-FRBCS VR. NAGARAJAN* & Dr. D. VIMAL KUMAR* 1 Research Scholar, Nehru Arts and Science College, and Assistant Professor, PG & Research Department of Computer Science, Shri Narayana Guru College, Coimbatore, Tamil 2 Professor & Head, Nehru Arts and Science College, Coimbatore, Tamil Nadu, India, ABSTRACT Prediction of diseases at an early stage is the most effective way of increasing the survival rate of people. Various data mining techniques have been proposed for early prediction of disease. One of the most efficient methods for disease prediction is Auto tuned hybridized Firefly and Differential search evolution Optimization Algorithm with Heterogeneous Fuzzy Rule-Based Classification System (AFDOA-Hetro-FRBCS). In FDOA-Hetro-FRBCS, the most representative features in the dataset were selected using a hybridized optimization algorithm and its randomness parameters are fine tuned by AFDOA. The selected features were given as input to Hetro-FRBCS which generates rules for disease prediction. However, the value of membership degree used in FRBCS might include uncertainty. In order to solve the uncertainty problem in AFDOA-Hetro-FRBCS, Type-2 FRBCS (T2FRBCS) is proposed for disease prediction. In T2FRBCS, the value of membership function is given by a fuzzy set that increases the fuzziness of a relation. Hence it has the ability to handle the inexact information in a logically correct manner. One of the processes in T2FRBCS is type reduction (TR) it represents a single value as a representative of the uncertainty. In this paper, composite Trapezoidal rule with Weighted Enhanced Karnik-Mendel (TWEKM) and composite Simpson rule with WEKM (SWEKM) methods are used to perform TR for TFRBCS. It enhanced the defuzzification process in TFRBCS. The whole process is named as AFDOA-Hetro-Type-2 with TWEKM FRBCS (AFDOA-Hetro-T2TFRBCS) and AFDOA-Hetro-Type-2 with SWEKM FRBCS (AFDOA-Hetro- T2SFRBCS) those enhanced the accuracy of disease prediction by solving the uncertainty problem. Keywords: Disease prediction, data mining, type-2 fuzzy set, Trapezoidal rule with Weighted Enhanced Karnik-Mendel, composite Simpson rule with Weighted Enhanced Karnik-Mendel. 1. INTRODUCTION Exact review of medical data supports early detection of diseases through big data development [1] in scientific and healthcare sectors. By applying data mining techniques in big data brings a new dimension for early detection of disease. It has the capability to handle huge volume of clinical data. Researchers have now investigated increasing ways of implementing data mining of clinical data to predict diseases reliably. The irrelevant features in the clinical dataset affect the performance of early disease prediction. Moreover, the irrelevant features lead to high computational complexity. Hence, a good collection of features is important for the high accuracy of disease prediction. In order to select the most representative features from the clinical dataset, a Modified Differential Evolution (MDE) [2] was proposed. However, this method consumes more time for feature selection because of using a large population to handle the premature convergence problem in MDE. This problem was resolved by using Firefly Optimization Algorithm (FOA) [3] to select the discriminative features and it was implemented in Map Reduce framework to further reduce the consumption time for feature selection. The selected features were given as input to the Naïve Bayes (NB), C4.5 and Random Forest (RF) classifiers to predict lung cancer, leukemia and heart disease. Two different methods [4] were proposed to further enhance disease prediction accuracy. One of the methods is FOA-Homo-FRBCS where only RF classifier was used in all mappers for disease prediction whereas in another method FOA-Hetro-FRBCS different classifier such as RF, Bayesian Tree and NeuroTree were used in all mappers for disease prediction. The FOA has slow convergence ISSN: 2005-4238 IJAS 2549 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 problem which was solved by AFDOA-Hetro-FRBCS [5] where HFDOA was used for feature selection and AFDOA was fine tuned by AFDOA. It enhanced the feature selection process and disease prediction accuracy effectively. However, the FRBCS used type-1 fuzzy logic system which leads to uncertainty problem. In this paper, Type-2 FRBCS (T2FRBCS) method is introduced to minimize the effects of uncertainties in FRBCS. This method is appropriate to incorporate uncertainty regarding membership into fuzzy set theory. When there is no uncertainty, a type-2 fuzzy set reduced to type-1 fuzzy set by TR process. Here, TWEKM and SWEKM methods are used to perform TR. The TWEKM and SWEKM effectively compute the centroids end points of T2FRBCS that used to reduce the fuzzy sets. Based on the rule generated by T2TFRBCS and T2SFRBCS, the lung cancer, leukemia and heart disease are predicted. 2. LITERATURE SURVEY Ahmed et al. [6] proposed a lung cancer prediction system using data mining technique. The data from various diagnostic centers was collected. Then, the data were pre-processed and clustered by k-means clustering which identified the relevant and non-relevant data. Finally, the lung cancer patients were predicted by applying the AprioriTid and decision tree algorithm on relevant data. However, AprioriTid has the problem of high execution time and memory consumption. Bashir et al. [7] proposed a multi-layered classification framework for medical decision support system. It used combination of heterogeneous classifiers such as Support Vector Machine (SVM), Naïve Bayes (NB), Decision Tree using the Gini Index (DT-GI), Linear Regression (LR), K-Nearest Neighbor (kNN) and Decision Tree with Information Gain (DT-IG) and Quadratic Discriminant Analysis (QDA) for disease prediction. It enhanced the disease prediction accuracy by using heterogeneous classifiers at multiple layers. However, there may be controversy results obtained from the heterogeneous classifiers which affect the efficiency of disease prediction. Daqqa et al. [8] proposed a prediction and diagnosis method using classification algorithm to predict leukemia disease. The primary objective of this method is to classify leukemia patients using DT, k-NN and SVM classification algorithms on the basis of patient’s fitness, gender and age level. This method still needs improvement in terms of accuracy. Mustaqeem et al. [9] proposed a hybrid model for cardiac disease prediction. This model was comprised of two phases are prediction model and recommendation model. Initially, Synthetic Minority Over-sampling Technique (SMOTE) was processed in the prediction model to balance the dataset and then the ambiguities and noise in the dataset were removed. After the selection of optimal features using attribute evaluation and ranker search algorithm, the selected features were processed in SVM, Multi-Layer Perceptron (MLP) and Random Forest (RF) classifiers to predict cardiac disease. Based on the prediction of cardiac disease, proper recommendation was given to the patients in recommendation model. The efficiency of this model would be further enhanced by analyzing the impact of individual features of patients. Purwanti & Calista [10] proposed an automatic detection of lymphocyte leukemia method to detect lymphocyte leukemia. Initially, the data were collected from peripheral blood smear single cell and the most representative features in the data were chosen using shape feature and histogram features. The selected features were given as input to the k-NN to classify the lymphocyte cells as normal lymphocytes and abnormal lymphocytes. However, the k values of kNN greatly influence the efficiency of automatic detection of lymphocyte leukemia disease. Mohan et al. [11] proposed an effective heart disease prediction technique called Hybrid Random Forest with Linear Model (HRFLM). It used all features in the dataset without any restriction of feature selection by making use of linear method and RF. Then, DT, language model, SVM, RF, NB and NN were used to predict heart disease. However, accuracy level of this prediction method is low. Ali et al. [12] proposed an expert system on the basis of stacked SVM for efficient prediction of heart disease. This system was comprised of two SVM models. The first SVM model minimized the feature coefficients to zero for removing the irrelevant features in the dataset. In the second SVM model, the pre- processed data were processed to predict the heart disease. Moreover, Hybrid Grid Search Algorithm (HGSA) was developed to fine tuned two SVM models which improved the accuracy of expert system. However, proper selection of kernel function is more difficult in SVM. ISSN: 2005-4238 IJAS 2550 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 3. PROPOSED METHODOLOGY In this section, the proposed AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro-T2SFRBCS are described in detail to predict different diseases. Initially, the clinical data are collected from different datasets. The collected data is split into small blocks equal to the number of mappers. In each mapper, AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro-T2SFRBCS are processed and the results of mappers are combined in the reducer for disease prediction. 3.1 Fuzzified the features using Type-2 Fuzzy Sets After the optimal selection of features using AFDOA, the type-2 fuzzy set is processed in each mapper to fuzzified the optimal features. A normal type-2 fuzzy set ̃ can be processed as a bivariate function on the Cartesian product, where the mapping is ̃ : × [0,1] → [0,1] is the universe of the primary feature, , of ̃, i.e., ̃ = {( , ), ̃ ( , )|∀ ∈ [0,1]} (3.1) Eq. (3.1) is often named the point-value expression of T2FRBCS, ̃ ( , ) can also denoted as ( ). A vertical slice of ̃ ( , ) is a secondary membership function which is given as follows: ′ ( ) ̃ ( = ′ , ) ≡ ̃ ( ′ ) = ∫ ∈[0,1] (3.2) ̃ In Eq. (3.2), ∫ represents union over all admissible. ( ) is a simplified version of ̃ ( ′ ). Eq. (3.1) is rewritten as, ̃( ) ̃ = ∫ ∀ ∈ (3.3) The two-dimensional support of ̃ ( , ) is termed as Footprint Of Uncertainty (FOU) of ̃. It is defined as follows: ( ̃) = {( , ) ∈ × [0,1]| ̃ ( , ) > 0} (3.4) In Eq. (3.4), ( ̃) is bounded by higher membership function ̅ ̃ ( ) and underneath membership function ̃ ( ). If ̃ ( ) denotes the -cut of ̃( ), ∈ [0,1], i.e., ̃( ) = { | ( ) ≥ } = [ ( ), ( )] (3.5) For any feature ∈ , ̃( ) is treated as the following -cuts decomposition which is defined as follows, ̃( ) = ⋃ [ ] = sup [ ] ̃ ( ) ̃ ∀ ∈[0,1] ( ) ∀ ∈[0,1] = sup [ / ( ), ( ))] (3.6) ∀ ∈[0,1] In Eq. (3.6), ∪ denotes the union operation and sup denotes the supremum. The vertical slices representation of ̃ could be obtained by applying Eq. (3.6) in (3.3) as {⋃∀ ∈[0,1][̃ ( )]} ̃ = ∫∀ ∈ (3.7) Based on the above analyses, the -planes representation of ̃ can be expressed as, {∫ [ ̃ ( ) ∀ ∈ ]} ̃ = ⋃∀ ∈[0,1] (3.8) In Eq. (3.8), the -plane ̃ is the union of primary membership functions of ̃ whose secondary membership degrees must be greater than or equal to i.e., ̃ = {( , ), ̃( ) ( ) ≥ |∀ ∈ , ∀ ∈ [0,1]} (3.9) The Eq. (3.9) is also expressed as, ̃ = ∫∀ ∈ ∫∀ ∈[0,1]{( , )| ̃( ) ( ) ≥ } (3.10) Eq. (3.9) and Eq. (3.10) denote both the point-value and continuous forms, and ̃ can also be expressed as, ISSN: 2005-4238 IJAS 2551 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 ̃ ( ) [ ( ), ( )] ̃ = ∫∀ ∈ = ∫∀ ∈ (3.11) Moreover, an -plane which is raise to the -level is generally represented as ̃ , i.e., ̃ = ̃ (3.12) In Eq. (3.12), ̃ is an Type-2 fuzzy set of FRBCS whose secondary membership values equal to . A type-2 fuzzy set can be completely distinguished by its higher membership function and underneath membership function. 3.2 Rule generation using Type-2 Fuzzy Logic Systems The fuzzified features are given as input to the RF, Bayesian Tree and NeuroTree which generates tree for disease prediction. Then, the rules are generated as ̃ and … is If 1 is ̃ , then is ̃ = 1,2, … (3.13) In Eq. (3.13), is the number of fuzzy rules, 1 ∈ 1 , … ∈ are optimized features, ̃ ( = 1,2, … ; = 1,2, … ) are the antecedent Type-2 fuzzy sets and ̃ ( = 1,2, … ) are consequent type-2 fuzzy sets. ̃ is used to denote the presence or absence of disease. If = ′ , only the vertical slice ̃ ( ′ ) of antecedent type-2 fuzzy sets ̃ is activated, whose -cut decomposition is ̃ ( ′ ) = sup [ ′ ′ ] (3.14) ∀ ∈[0,1] , ( ), , ( ) A firing interval is computed at the -level ̃ ( ′ ) for every fuzzy rule which is given as follows: ( ′ ) ≡ [ ( ′ ), ̅̅̅̅̅ ( ′ )] : ( ′ ) ≡ =1 , ( ′ ) (3.15) ̅̅̅̅̅ ( ′ ) ≡ , ( ′ ) { =1 In Eq. (3.15), represents the minimum or product t-norm operation. If that the -plane ̃ of the consequent Type-2 fuzzy sets at the -level is ̃ ( ) [ ( ), ( )] ̃ = ∫∀ ∈ = ∫∀ ∈ , , (3.16) After that, the firing interval of each fuzzy rules is intergraded with its corresponding consequent - plane ̃ to obtain the firing rule -plane ̃ , i.e., ( ̃ ) = [ ̃ ( | ′ ), ̅ ̃ ( | ′ )] ( ) ̃ : ̃ ( | ′ ) = ( ′ ) ∗ , (3.17) ′ ′ { ̅ ̃ ( | ) = ( ) ∗ , ( ) In Eq. (3.17), ∗ is the minimum or product operation. Then, combine all the ̃ ( = 1,2, … ) to get the output -plane ̃ which is given as follows: ( ̃ ) = [ ̃ ( | ′ ), ̅ ̃ ( | ′ )] ̃ = ̃ ( | ′ ) = ̃ ( | ′ ) ∨ … ∨ ̃ ( | ′ ) (3.18) ′ ′ ′ { ̅ ̃ ( | ) = ̅ ̃ ( | ) ∨ … ∨ ̅ ̃ ( | ) In Eq. (3.18), ∨ denotes the maximum operation. The Type-2 fuzzy sets are mapped into a Type-2 fuzzy set into Type-1 fuzzy set for defuzzification process. The centroids of ̃ is computed to type-reduction (TR) set at the -level which is given as follows: , ( ′ ) = ̃ ( ′ ) = ′ ′ (3.19) ̃ ( ), [ ̃ ( )] In Eq. (3.19), ∈ [0,1] and the two end points ̃ ( ′ ) and ̃ ( ′ ) can be computed by EKM algorithm [13] as, ISSN: 2005-4238 IJAS 2552 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 ∑ ̃ ( ) =1 ̃ ( ′ ) = min ∑ (3.20) ̃ ( ) =1 ̃ ( ), ̃ ( )∈{ ̅ ̃ ( )} and ∑ ̃ ( ) =1 ̃ ( ′ ) = max ∑ (3.21) ̃ ( ) =1 ̃ ( ), ̃ ( )∈{ ̅ ̃ ( )} In Eq. (3.21), represents the number of discrete points of the rule consequent primary variable. To compute ̃ ( ′ ) and ̃ ( ′ ), WEKM algorithm is used which is given as follows, WEKM algorithm for ̃ ( ′ ) 1. Assign = [2.4] 2. Calculate = ∑ =1 ̅ ̃ ( ) + ∑ = +1 ̃ ( ), = ∑ =1 ̅ ̃ ( ) + ∑ ′ = +1 ̃ ( ) and = 3. Find ′ ∈ [1, − 1] such that ′ ≤ ′ ≤ ′ +1 4. If ( ′ == ) 5. Assign ′ = ̃ ( ′ ) and = 6. else max ( , ′ ) 7. Calculate = ( ′ − ) and ′ = + ∑ =min( , ′ )+1 [ ̅ ̃ ( ) − ̃ ( )], ′ = + max ( , ′ ) ′′ ( ′ ) ′ ∑ =min( , ′ )+1 [ ̅ ̃ ( ) − ̃ ( )], = ′ ′ ′′ ( ), ′ ′ 8. Assign = = and = 9. Go to step 3 10. end if WEKM algorithm for ̃ ( ′ ) 1. Assign = [1.7] 2. Calculate = ∑ =1 ̃ ( ) + ∑ = +1 ̅ ̃ ( ), = ∑ =1 ̃ ( ) + ∑ ′ = +1 ̅ ̃ ( ) and = 3. Find ′ ∈ [1, − 1] such that ′ ≤ ′ ≤ ′ +1 4. If ( ′ == ) 5. Assign ′ = ̃ ( ′ ) and = 6. else max ( , ′ ) 7. Calculate = ( ′ − ) and ′ = − ∑ =min( , ′ )+1 [ ̅ ̃ ( ) − ̃ ( )], ′ = − max ( , ′ ) ′′ ( ′ ) ′ ∑ =min( , ′ )+1 [ ̅ ̃ ( ) − ̃ ( )], = ′ ′ ′′ ( ), ′ ′ 8. Assign = = and = 9. Go to step 3 10. end if In the above WEKM algorithm, a composite trapezoidal rule and composite Simpson rule are used to integrate the rules. Such algorithms are named as TWEKM and SWEKM respectively. value used in TWEKM is given as follows, 1 , = 1, = {2 (3.22) 1, ≠ 1, value used in SWEKM is given as follows 1 2 , = 1, = {1, = 1 (2)& ≠ 1, (3.23) 2, = 0 (2)& ≠ ISSN: 2005-4238 IJAS 2553 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 In TWEKM and SWEKM, and are the switching points for the underneath and higher membership functions and ̃ ( ′ ) and ̃ ( ′ ) are the left and right end points of the centroids interval respectively. Finally, all the -planes are combined to constitute Type-1 fuzzy sets which is given as follows, = sup ( ′ ) (3.24) ∀ ∈[0,1] The value of is uniformly split into alpha-planes at 1 , 2 , … . Then the crisp output of Type-2 FRBCS is calculated as, ( ′ ) = ∑ =1 [( ̃ ( ′ ) + ̃ ( ′ )) /2] / ∑ =1 (3.25) Eq. (3.25) is the average of end points defuzzication method. Thus, the Type-2 FRBCS with TWEKM and SWEKM fuzzified and defuzzified the clinical data for disease prediction. 4. Result And Discussion The performance of AFDOA-Hetro-FRBCS, AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro- T2SFRBCS are tested in terms of accuracy, precision, recall and f-measure. Here, the lung cancer, leukemia, and heart disease datasets [5] are used to test the existing and proposed disease prediction methods. 4.1 Accuracy Accuracy is the fraction of correct disease predictions over the total number of instances evaluated. It is calculated as, ( ) + ( ) = + ( ) + + ( ) where, is actual positive data (i.e., presence of disease) which are exactly predicted as positives, is the actual negative data (i.e., absence of disease) which are predicted exactly as negatives, is known negative data which are wrongly predicted as positives and is known positive data which are wrongly predicted as negatives. Figure 4.1 Evaluation of Accuracy The accuracy of AFDOA-Hetro-FRBCS, AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro-T2SFRBCS methods for different datasets is shown in Figure 4.1. For the heart disease dataset, the accuracy of AFDOA-Hetro-T2SFRBCS method is 1.12% greater than AFDOA-Hetro-FRBCS and 0.41% greater ISSN: 2005-4238 IJAS 2554 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 than AFDOA-Hetro-T2TFRBCS method. From this analysis, it is proved that the AFDOA-Hetro- T2SFRBCS has high accuracy than other methods. 4.2 Precision It is used to measure the positive patterns that are correctlyfrom the total predicted patterns in a positive class. It is calculated as, = ( + ) Figure 4.2 Evaluation of Precision The precision of AFDOA-Hetro-FRBCS, AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro- T2SFRBCS methods for different datasets is shown in Figure 4.2. For the heart disease dataset, the precision of AFDOA-Hetro-T2SFRBCS method is 0.82% greater than AFDOA-Hetro-FRBCS and 0.41% greater than AFDOA-Hetro-T2TFRBCS method. From this analysis, it is proved that the AFDOA-Hetro-T2SFRBCS has high precision than other methods. 4.3 Recall It is used to measure the fraction of positive patterns that are correctly predicted. It is calculated as, = ( + ) ISSN: 2005-4238 IJAS 2555 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 Figure 4.3 Evaluation of Recall The recall of AFDOA-Hetro-FRBCS, AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro-T2SFRBCS methods for different datasets is shown in Figure 4.3. For the heart disease dataset, the recall of AFDOA-Hetro-T2SFRBCS method is 1.13% greater than AFDOA-Hetro-FRBCS and 0.41% greater than AFDOA-Hetro-T2TFRBCS method. From this analysis, it is proved that the AFDOA-Hetro- T2SFRBCS has high recall than other methods. 4.4 F-measure It represents the harmonic mean of precision and recall. It is calculated as, . − = 2. + ISSN: 2005-4238 IJAS 2556 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 Figure 4.4 Evaluation of F-measure The F-measure of AFDOA-Hetro-FRBCS, AFDOA-Hetro-T2TFRBCS and AFDOA-Hetro- T2SFRBCS methods for different datasets is shown in Figure 4.4. For the heart disease dataset, the F- measure of AFDOA-Hetro-T2SFRBCS method is 1.44% greater than AFDOA-Hetro-FRBCS and 0.71% greater than AFDOA-Hetro-T2TFRBCS method. From this analysis, it is proved that the AFDOA-Hetro-T2SFRBCS has high F-measure than other methods. 5. CONCLUSION In this paper, the prediction accuracy of FRBCS based disease prediction method is further enhanced by Type-2 fuzzy rule system. In T2FRBCS, primary membership and secondary membership function to solve the uncertainty problems. The secondary membership function increases the fuzziness of a relation by using the value of membership function given by a fuzzy set. TR is used for the representation between Type-2 fuzzy set and Type-1 fuzzy set. It is achieved by using Type-2 Trapezoidal FRBCS and Type-2 Simpson FRBCS. It enhances the defuzzication process. Based on AFDOA-Hetro- T2TFRBCS and AFDOA-Hetro-T2SFRBCS, rules are generated for lung cancer, leukemia and heart disease prediction. The experimental results prove that the AFDOA-Hetro-T2SFRBCS method has high accuracy, precision, recall and f-measure than other methods for disease prediction. REFERENCES [1] Wang, L., & Wang, L. (2017). Disease Prediction by Machine Learning Over Big Data From Healthcare Communities. IEEE Access, 5, 88869-8879. [2] Vivekanandan, T., & Iyengar, N. C. S. N. (2017). Optimal feature selection using a modified differential evolution algorithm and its effectiveness for prediction of heart disease. Computers in biology and medicine, 90, 125-136. [3] Nagarajan, V. R., & Kumar, V. (2018). An optimized sub group partition based healthcare data mining in big data. International Journal for Innovative Research in Science & Tehnology (IJRST), 4(10), 79-85. [4] Nagarajan, V. R., & Kumar, V. (2019). An ensemble big data classification for healthcare data predication analysis. European Journal of Business & Social Sciences, 7(6), 160-172. [5] Nagarajan, V. R., & Kumar, V. (2019). Hybridized firefly and differential evolution optimization algorithm based feature selection for disease prediction. International Journal of Scientific & Technology Research, 8(10), 218-224. [6] Ahmed, K., Kawsar, A. A., Kawsar, E., Emran, A. A., Jesmin, T., Mukti, R. F., & Ahmed, F. (2013). Early detection of lung cancer risk using data mining. Asian Pacific Journal of Cancer Prevention, 14, 595-598. [7] Bashir, S., Qamar, U., Khan, F. H., & Naseem, L. (2016). HMV: A medical decision support framework using multi-layer classifiers for disease prediction. Journal of Computational Science, 13, 10-25. [8] Daqqa, K. A. A., Maghari, A. Y., & Al Sarraj, W. F. (2017, May). Prediction and diagnosis of leukemia using classification algorithms. In Information Technology (ICIT), 2017 8th International Conference on (pp. 638-643). IEEE. [9] Mustaqeem, A., Anwar, S. M., Khan, A. R., & Majid, M. (2017). A statistical analysis based recommender model for heart disease patients. International journal of medical informatics, 108, 134-145. [10] Purwanti, E., & Calista, E. (2017, May). Detection of acute lymphocyte leukemia using k- nearest neighbor algorithm based on shape and histogram features. In Journal of Physics, 853(1), 012011). IOP Publishing. [11] Mohan, S., Thirumalai, C., & Srivastava, G. (2019). Effective heart disease prediction using hybrid machine learning techniques. IEEE Access, 7, 81542-81554. ISSN: 2005-4238 IJAS 2557 Copyright ⓒ 2020 SERSC
International Journal of Advanced Science and Technology Vol. 29, No.02, (2020), pp. 2549-2557 [12] Ali, L., Niamat, A., Golilarz, N. A., Ali, A., & Xingzhong, X. (2019). An Optimized Stacked Support Vector Machines based expert system for the effective diagnosis of heart disease. IEEE Access, 7, 54007-54014. [13] Wu, D., & Mendel, J. M. (2008). Enhanced karnik--mendel algorithms. IEEE Transactions on Fuzzy Systems, 17(4), 923-934. ISSN: 2005-4238 IJAS 2558 Copyright ⓒ 2020 SERSC
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