Oral Health Newsbites - National Dental Centre of Singapore

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Oral Health Newsbites - National Dental Centre of Singapore
Oral Health Newsbites
                                                            ISSUE 1 | MAY 2022

        P3                    P4                                  P6
   New automatic       The link between                  Education Day 2021
 RPD design system     periodontitis and                    andORH ACP
    for partially      risk of gestational                  Excellence in
 edentulous patients        diabetes                      Teaching Awards

                                      Oral Health Newsbites | Issue 1 May 2022   1
Oral Health Newsbites - National Dental Centre of Singapore
Oral Health Newsbites is a bi-annual newsletter which highlights our key innovations and events
under clinical research and education. In this first issue, we share some of the meaningful work
and achievements of our clinicians, researchers, and educators who have contributed to the
future of patient care and innovation.

The SingHealth Duke-NUS Oral Health Academic Clinical Programme (ORH ACP) was
launched in August 2014. The ORH ACP brings together three clinical departments and six
specialties across National Dental Centre Singapore (NDCS), KK Women’s & Children’s Hospital
(KKH), SingHealth Polyclinics (SHP) and Changi General Hospital (CGH). ACP’s main priorities include
focusing on the four key Research Themes (Bone Bioengineering, Oral Devices and Therapeutics,
Genomics / Biomarker Discovery and Health Services Research), nurturing budding clinician
scientists, as well as collaborating with Duke-NUS on joint certification of Senior Residency and
Fellowship Programs.

                                               CLINICAL INNOVATION

                                       3       New automatic RPD design system
                                               for partially edentulous patients

                                               PanoShield: Face shields that offer
                                               panoramic protection

                                               RESEARCH

                                       4       The link between periodontitis and
                                               risk of gestational diabetes

Contents                               5       A counterfactual approach onthe
                                               effect of metabolic syndrome on
                                               tooth loss: a population-based study

                                               EDUCATION

                                       6       Education Day 2021 and ORH ACP
                                               Excellence in Teaching Awards

                                               OVERVIEW
                                       7       FY21 Grant and Award Recipients

2   Issue 1 May 2022 | Oral Health Newsbites
Oral Health Newsbites - National Dental Centre of Singapore
CLINICAL INNOVATION

New automatic RPD design system for partially edentulous patients
A more pleasant patient journey for denture wearers

N
      DCS, together with               service and meet the                                                design patterns to fit the
      A*STAR and ST                    rising demands of denture                                           geometry of the patient.
      Engineering, developed a         production for Singapore’s
software prototype to generate         ageing population.                                                  The team proposed using a
printable, patient-specific                                                                                selective laser melting (SLM)
Removeable Partial Dentures            The three-step system                                               technique to mass produce
(RPD) framework file from              encompasses of the                                                  the Chrome-cobalt denture
intra-oral scans, automatically.       automated tooth identification,                                     frame precisely. It could
The new automatic RPD design           digitisation of RPD design                                          potentially improve the
system aims to reduce the              and RPD voxelisation, the                                           efficiency of denture production,
time spent on denture                  SmartRPD software will                                              enhance the quality of treatment
production, improve the                automatically process teeth                                         and patient experience, and
throughout of the denture              configurations and generate                                         reduce cost.

                                                    NDCS/NDRIS Stakeholders

                                                                                                 Dr Yu Na
                                    Dr Seetoh Yoong Liang                                       Clinician Scientist &
                                    Head & Senior Consultant                                     Principal Investigator
                                    Prosthodontic Unit                                           Senior Dental Surgeon
                                    Department of Restorative                                    Prosthodontics Unit
                                    Dentistry, NDCS                                              Department of Restorative Dentistry,
                                                                                                 NDCS

         Partners:       Temasek Holdings (Funder)                          A*STAR (Partner)                        ST Engineering (Partner)

PanoShield: Face shields that offer panoramic protection
Enhancing safety for healthcare workers

C
       linicians who perform                The PanoShield is developed with the aims of enhancing
       aerosol-generating                   peripheral protection, being compatible with essential
       procedures are                       supporting devices required by various clinical sub-specialties,
recommended to don Personal                 and improving the user’s comfort level.
Protective Equipment (PPE)
including gloves, protective           It can be worn over existing PPE, is universally fitting, comfortable
outerwear, a face shield, and          and secure for long hours, has anti-fogging properties and is
N95 masks, to prevent direct           easily scalable for manufacturing.
deposition of respiratory
droplets on their faces.                                                                                      Adjustable size
However, it was found that                                                             Flexible
                                                                                      coverage
there are protection gaps
despite such PPE measures –
ineffective protection against
fine respiratory droplets/
aerosols, inadequate periphery                                                                                                           Anti-fog
                                                                                                                                         coating
protection, obtrusive operational
constraint, and doffing risks.
                                                    NDCS/NDRIS Stakeholders

                                     Dr Yu Na
                                     Clinician Scientist &                                     Dr Constance Teo Ee Hoon
                                     Principal Investigator                                    Senior Consultant, Department of
                                     Senior Dental Surgeon                                     Otorhinolaryngology – Head and Neck
                                     Prosthodontics Unit                                       Surgery, SGH Head, SingHealth
                                     Department of Restorative Dentistry,                      Duke-NUS Head and Neck Centre
                                     NDCS

                      Partners:           SingHealth Medical Technology Office (SingHealth MTO)

                                                                                  Oral Health Newsbites | Issue 1 May 2022                          3
Oral Health Newsbites - National Dental Centre of Singapore
RESEARCH

The link between periodontitis and
risk of gestational diabetes
Congratulations to Dr Preethi Prajod, who was awarded
the NMRC Clinician Scientist Individual Research Grant -
New Investigator Grant (CNIG) in 2020.

F
     or the past few years, Dr Preethi has been              treating periodontal
     working on the functional attributes of                 disease before and during
     microbiota and immune responses at the                  pregnancy may reduce
intersection of oral-systemic health. Backed                 maternal and perinatal
with this funding, her research study would                  morbidity associated with GDM and
examine the prospective association between                  prevent type 2 diabetes after pregnancy.
periodontitis and the risk of Gestational
                                                             Most women do not seek oral health care during
Diabetes Mellitus (GDM) in pregnant women.
                                                             pregnancy despite evidence that poor oral
One in every five pregnant women in Singapore
                                                             health can adversely impact the health of a
have been observed to develop GDM. Women                     pregnant woman and her child. Concern about
with GDM are at increased risk for foetal and                the safety of dental services during pregnancy
maternal complications and are also associated               restrict their visit to clinics. The strategy to
with about seven-fold increased risk for                     change the perception of pregnant women is
developing type 2 diabetes mellitus in later life.           to include dental health education as an integral
                                                             part of prenatal health care. To potentiate
Periodontitis is treatable. If periodontal disease           general health and well-being, women should
is confirmed as a risk factor for GDM through                routinely be counselled about the safety
this initiative, it will open doors to intervention          and maintenance of good oral health habits
studies to prevent GDM. Improving oral health and            throughout their pregnancy.

                                                 NDCS/NDRIS Stakeholders

                                                                            A/Prof Chaminda
                                      Dr Preethi Prajod                     Jayampath
                                      Research Fellow,                      Seneviratne
                                      ORH ACP NDRIS                         Adjunct Professor
                                                                            NDCS

    Partners:     KK Women’s and Children’s Hospital (KKH)          Academic Center for Dentistry Amsterdam (ACTA)

4    Issue 1 May 2022 | Oral Health Newsbites
Oral Health Newsbites - National Dental Centre of Singapore
RESEARCH

A counterfactual approach on t he effect of
metabolic s yndrome on tooth loss:
a population-based study
The link between oral                               This analysis was based on
and general health is by                            data from a cohort study
                                                    (2009–2014) with adults aged
default bidirectional, which                        20+ from Southern Brazil. MetS
makes the establishment                             (exposure), lack of functional
of causality a core issue in                        dentition and number of
health research. Prof Marco                         lost teeth (outcomes) were
                                                    assessed using self-reported,
Peres’ and his team’s findings,                     lab and clinical data. Possible
based on cutting-edge                               confounders included sex, age,                           weights (a counterfactual
epidemiological tools, provide                      family income, educational                               analytical method) was also
                                                    level, smoking status and sugar                          used to enhance group
evidence on the effect of                                                                                    comparability and estimate
                                                    consumption. The effect of MetS
Metabolic Syndrome (MetS)                           on the outcomes was estimated                            causal effects. Data imputation
on tooth loss.                                      using conventional logistic or                           was used to deal with missing
                                                    negative binomial regression                             values. E-value was used to
MetS and tooth loss are prevalent                                                                            assess the effect of unmeasured
                                                    models. Marginal structural
conditions that negatively                                                                                   confouders.
                                                    modeling (MSM) with stabilized
affect health and quality of life,
increases the cost of health
care systems, and exacerbates                          1,283 participants had available information for the outcomes.
social problems and inequalities.                      Individuals with MetS were more likely to experience a lack of
Even though some studies have                          functional dentition than those without MetS [odds ratio (OR)
addressed the association                              from logistic regression 1.7, 95% CI 1.0-2.9; OR from MSM 3.2, 95%
between MetS and tooth loss, the                       CI 2.3-4.6]. Moreover, the number of teeth lost was 20% higher
investigation of this relationship                     in participants with MetS compared to those without MetS in
using an appropriate statistical                       conventional analysis (mean ratio [MR] 1.2, 95% CI 1.1- 1.3). The
approach and a representative                          MR increased to 1.7 (95% CI 1.5-2.0) when using MSM.
sample of the population remains
unexplored in the literature.

This study aimed to investigate                        Direct acyclic graphic for the                                                 • Smoking
the effect of MetS on tooth loss                       effect of MetS on theoccurrence                                                  Status
                                                                                                                                        • Sugar
in a population-based sample. It                       of tooth loss.                                                                Consumption
                                                                                                                     • Sex
was hypothesised that MetS has                                                                                       • Age
an effect on tooth loss. Studying                      Exposure: Metabolic Syndrome                              • Income
                                                                                                             • Educational Level                      • Tooth Loss
this topic is essential to inform the                  Confounding factors: Sex,
best strategies to prevent tooth                       Age, Income, Educational
loss in populations with MetS and                      Level, Smoking Status, Sugar
                                                                                                                                      • Metabolic
to encourage public policies that                      Consumption                                                                    Syndrome

approach common risk factors to                        Outcome: Tooth Loss
oral and general health.

                                                            NDCS/NDRIS Stakeholders

                                                  Marco A. Peres                                         Karen G. Peres
                                                  Supervisor,                                            Co-supervisor,
                                                  NDRIS/NDCS,                                            NDRIS/NDCS,
                                                  Duke-NUS                                               Duke-NUS

 Partners:
             This study is part of    Marina Leite Souza                  Gustavo G. Nascimento                           David A. Gonzalez Chica
              the PhD thesis of      (PhD student, UFSC, Brazil);   (collaborator, Aarhus University, Denmark);   (collaborator, University of Adelaide, Australia)

                                                                                         Oral Health Newsbites | Issue 1 May 2022                                5
Oral Health Newsbites - National Dental Centre of Singapore
EDUCATION

Education Day                       The ORH ACP Excellence in Teaching Awards were conferred to:

2021 andORH
ACP Excellence                         AUXILIARY
in Teaching                           PROGRAMME

 Awards
                                       Dr Quek Heng Chuan
                                       Senior Consultant,
                                        Prosthodontic Unit,
                                        Department of
    Since 2015, Education Day
                                         Restorative Dentistry
    is an annual event held
    to commemorate our
    educators and learners.
    NDCS’s Education Day was
    held on 8 September last
    year, and comprised of a
    lunchtime talk by Dr Song Yi
                                       POST-GRADUATE
    Lin, Consultant, Department
    of Orthodontics, as well as        Dr Bien Lai
    the ORH ACP Excellence in          Head and Senior
    Teaching Awards.                    Consultant,
                                         Paediatric Dentistry
Dr Song’s talk – The Science             Unit,Department of
of Learning – delved into              Restorative Dentistry
methods to optimise the
learning process, make it
easier to learn, remember,
and apply knowledge.

The event was followed by a virtual Faculty Development Workshop, titled “Introduction to Team
Based Learning Pedagogy”. It was facilitated by Dr Foo Lean Heong, Consultant, Periodontic Unit,
Department of Restorative Dentistry, and Dr Chan Pei Yuan, Consultant, Endodontic Unit, Department
of Restorative Dentistry.

6     Issue 1 May 2022 | Oral Health Newsbites
Oral Health Newsbites - National Dental Centre of Singapore
FY21 Grant and Award Recipients
          FY2021 Grants and Recipients

                                        Grant                               Recipient
            GLOBICS: The Global consortium of Oral health-related
                                                                      A/Prof Karen Peres
            Birth Cohort Studies

            Temasek Foundation Public Health Innovations Grant        Dr Yu Na

            A*STAR Industry Alignment Fund - Industry Collaboration
                                                                      Cl A/Prof Goh Bee Tin
            Projects (IAF-ICP)

            Clinicial Scientist Award                                 Dr Yu Na

          FY2021 Awards and Recipients

                                        Award                               Recipient

            Duke-NUS Hall of Master Academic Clinicians 2022          Cl A/Prof Goh Bee Tin

            SingHealth Publish! Award 2021                            A/Prof Jaya Seneviratne

            Singapore Health Quality Service Award                    Cl A/Prof Chew Ming Tak

                                 Scan this QR code for more information
                                   about NDCS research publications.

                             ndcs.sg               ndcs-sg            ndcs-sg

                                                www.ndcs.com.sg

7   Issue 1 May 2022 | Oral Health Newsbites
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