Learning Psychedelic-Assisted Psychotherapy

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Learning Psychedelic-Assisted Psychotherapy
Learning Psychedelic-Assisted
               Psychotherapy

                Dr. Janis Phelps, Director
      Center for Psychedelic Therapies & Research

                       Presentation for
Meditation and Psychotherapy: Learning from Non-Ordinary States
      Cambridge Health Alliance/Harvard Medical School
                         May 1, 2021
Learning Psychedelic-Assisted Psychotherapy
DISCLOSURES

  − The presenter certifies that there are no actual
    or potential conflicts of interest in relation to
    this presentation.

  − This presentation discusses only legal and FDA-
    approved uses of psychedelic medicines.
Learning Psychedelic-Assisted Psychotherapy
WHY CREATE ACADEMIC TRAINING
        PROGRAM IN PSYCHEDELICS?

─ Upsurge of clinical & public interest in last 10 years

─ Demonstrated therapeutic efficacy for several medical
  indications

─ Need for clinicians trained in this modality

─ Demand for public education on risk minimization with
  psychedelic usage
Learning Psychedelic-Assisted Psychotherapy
Current State of Research on Psilocybin and MDMA

  • FDA has approved Phase 3 research for MDMA for PTSD

     o MAPS is approaching the end of the research in this
       phase in next 9 months
     o Many predict that the FDA is likely to approve this
       medicine for PTSD in mid to late 2022

  • FDA has approved Phase 2 research for Psilocybin for
    Intractable Depression and Major Depression

     o Phase 3 research will follow and likely conclude in 2023-
       2024
Learning Psychedelic-Assisted Psychotherapy
MDMA Long-Term PTSD Outcome Study
                Findings

Goals:
         • Measured 12-month effects of MDMA-Assisted
           Therapy for PTSD in First-Responders and
           Veterans

Outcomes: (p
Learning Psychedelic-Assisted Psychotherapy
Summary of Psilocybin Findings

• Safety established:                                               •    Mystical Experience induced by
    • No medical or psychiatric SAEs                                     psilocybin:
    • AE: Mild elevation BP                                                •   Mystical Experience mediated
    • HA 28%; Nausea 14%                                                       improved clinical outcomes
• Feasibility established                                           •    Spiritually significant and meaningful
• Rapid acting anxiolytic and anti-                                      experiences
  depressant effects:                                               •    Decreased existential distress:
    • Large magnitude of improvement                                       • Demoralization
    • Approximately 60-80% of                                              • Hopelessness
      participants continued with                                   •    Improved quality of life, spiritual well
      clinically significant reductions in
      depression or anxiety                                              being, mood, behavior; death
                                                                         transcendence (self-rated positive
• Sustained anxiolytic and anti-                                         attitudes about death)
  depressant effects:
                                                                    •    Overwhelmingly positive response from
    • at least 7 weeks and up to 4.5
      years in second follow-up                                          public and media
                                                                    •    2016 press release >1.5 billion views

      Ross S. et al. Rapid and sustained symptom reduction following psilocybin treatment for anxiety and
      depression in patients with life-threatening cancer: a randomized controlled trial. J of Psychopharmacology.
      2016 (12):1165-1180.

      Agin-Liebes, G. et al. Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential
      distress in patients with life-threatening cancer. J. of Psychopharmacology. 2020, 34(2): 155-166.
Learning Psychedelic-Assisted Psychotherapy
ELEMENTS OF AN IDEAL 150-HOUR
           TRAINING CURRICULUM

─   Training in FDA-approved legal psychedelic research
    and therapy

─   Academically accredited post-graduate training

─   For licensed and ordained mental health trainees

─   Partnered with MDMA and psilocybin research orgs

                                                     © CIIS 2020
Learning Psychedelic-Assisted Psychotherapy
Guidelines for the Training
Learning Psychedelic-Assisted Psychotherapy
Eligibility for Training
            in Post-Graduate Certificate

─ Clinical and Counseling Psychologists
─ Physicians and Psychiatrists
─ Ordained/Commissioned Clergy and Chaplains
─ Registered Nurses and Nurse Practitioners
─ Naturopathic Doctors
─ Physician Assistants
─ Licensed Professional Clinical Counselors
─ Marriage and Family Therapists and Clinical Social Workers
─ Occupational Therapists
─ Advanced Alcohol and Drug Counselors
─ Traditional Chinese Medicine practitioners
─ Physical Therapists
Learning Psychedelic-Assisted Psychotherapy
12 Domains of Training
 1. The history of clinical research and current legal status of
    psychedelic-assisted therapy
 2. Neurobiology, neuropharmacology, drug disposition and drug
    interactions
 3. Best practices in sets and settings: Preparation, psychedelic
    session and integration
 4. Psychedelics and therapeutic relationships: Transference,
    boundaries, ethics and self-care
 5. Supervised observation of psychedelic session videos
 6. Variations in therapeutic models: Client-centered and
    psycholytic psychedelic therapy
                                                       Phelps (2017 & 2019)
12 Domains of Training
  7. Complementary therapeutic techniques in psychedelic-
     assisted therapy
  8. Co-therapy methods and inter-professional skills for working
     on multidisciplinary teams
  9. Current models of consciousness, transpersonal intelligence
     and mystical experiences
 10. Ceremonial use of psychedelics in religious and community
     settings
 11. Individual and group clinical supervision during an internship
 12. Personal experience of being guided as a research
     participant in an FDA-approved study
                                                      Phelps (2017 & 2019)
Philosophical Background
Safety in Psychedelic Sessions
Mentoring and Assessment

Mentoring with Senior Researchers and Clinicians
• 9 hours of group and individual mentor consultation

Assessments: Formative and Summative
• Trainees assessed at interview
• Assessed trainee progress at 6 and 12 months
• Mentors and trainees complete program evaluations

Required Papers
• Trainees write monthly process papers
• Final paper summarizing learning or a publishable article
Psychedelic Therapist Competencies

ü An empathetic abiding presence
ü
ü Trust enhancement

ü Transpersonal intelligence

ü Knowledge of the physical and psychological effects
  of psychedelics

ü Therapist self-awareness and ethical integrity

ü Proficiency in complementary techniques
Freud posits an optimal
      attentional stance | mindful state

Freud repeatedly admonishes the analyst to
"suspend . . . judgment and give . . . impartial
attention to everything there is to observe”:

a) the absence of reason or deliberate attempts
   to select, concentrate or understand

b) even, equal and impartial attention to all that
   occurs within the field of awareness

~ Mark Epstein On Evenly Suspended Attention
Mindfulness and Meditation:
Key Practices for Therapists and Clients Alike

                      Meditation is probably the best
                      preparation for a psychedelic session.

                      Those who have spent time in the
                      solitary attempt to manage the mind, to
                      eliminate thought, and to reach higher
                      states of concentration, are the best
                      candidates.

                      When the ego-loss state occurs, they are
                      ready. They recognize the process as an
                      end eagerly awaited.

                      — Leary, Metzner and Alpert (1962)
Mindfulness and Mystical Experiences:
Protective Factors against Self-Importance

 The mystical experience, whether induced by
 chemicals or other means, enables the
 individual to be so peculiarly open and
 sensitive to organic reality that the ego begins
 to be seen for the transparent abstraction that
 it is.

       — Alan Watts in The Joyous Cosmology
                                     (1962)
Huxley’s Ontological Response

   Maybe it is private and there’s no unitive knowledge of
   anything but one’s own physiology.

   Who cares?

   The fact remains that the experience can open one’s
   eyes and make one blessed and transform one’s whole
   life.

                              ~ Aldous Huxley in Islands
Demographics of 2016 - 2020 Trainees
                               98   MDs, NDs, PAs, and Pharmacists
                               50   Clinical Psychologists
                               61   Marriage/Family Therapists and LPCCs
   296 Professionals           35   Nurses
Licensed average of 15 years   41   Social Workers
                               7    Clergy and Chaplains
                               2    Traditional Chinese Medical Doctors
                               2    Physical / Occupational Therapists

 Average Age: 41 years
 Trainees Identified as People of Color: 28%
 Women: 51% Men: 45% Non-Binary: 4%
 Trainees Identified as LGBTQi: 21%
Expanded Access and
Risk Evaluation and Mitigation Strategies

    MDMA                            Psilocybin
Likely Risk Evaluation and Mitigation Strategies
            for Psilocybin and MDMA

   • Designated clinics with certified clinicians

   • Dyads of clinicians will provide therapies

   • Licensed clinician will be dyadic lead with a
     facilitator with a clinical BA, MS, and above

   • New models of delivery will be explored:
     e.g., groups, more integration therapy, family
     assessment
Necessary Training Initiatives

• Expansion of training programs to sites across the country

• Licensed curricular material to share with other
  universities

• FDA-approved training research for students in psilocybin
  and MDMA-assisted sessions

• Online Public Education programs on risk mitigation for
  psychedelics, particularly in decriminalized regions
The most beautiful and profound emotion we can
experience is the sensation of the mystical. It is the sower
of all true science.

… for whom this emotion is a stranger, who can no longer
wonder and stand rapt in awe, is as good as dead.

To know that what is impenetrable to us really exists,
manifesting itself as the highest wisdom and the most
radiant beauty, which our dull faculties can comprehend
only in their primitive forms.

                    ~ Albert Einstein, The Merging of Spirit
It is my great concern to separate psychedelics from the
ongoing debates about drugs, and to highlight the potential
inherent to these substances for self-awareness, as an
adjunct in therapy, and for fundamental research into the
human mind.

It is my wish that a modern Eleusis will emerge, in which
seeking humans can learn to have transcendent experiences
with sacred substances in a safe setting.

I am convinced that these soul-opening, mind-revealing
substances will find their appropriate place in our society
and our culture.

              ~ Albert Hofmann, in a letter from April, 2007
THANK YOU

          Dr. Janis Phelps, Director
Center for Psychedelic Therapies and Research
               www.ciis.edu/cptr

        Information: lpustarfi@ciis.edu
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